Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 6 , Pages 892-895 , June 2006

14C-Lidocaine Disposition in Serum and Tissues of Normal and Liver Diseased Rats

  • Theodosios Saranteas, MD, DDS, PhD

      Affiliations

    • Senior Research Fellow, Department of Pharmacology, Medical School, University of Athens, Athens, Greece; and Senior Resident, Department of Anesthesiology, General Hospital of Athens “G. Gennimatas,” Athens, Greece
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Saranteas: 19 Karatza str and Klemanso 18534 Piraeus, Athens, Greece
    • ,
  • Constantinos Mourouzis, MD, DDS, PhD

      Affiliations

    • Oral and Maxillofacial Surgeon and Senior Research Fellow, Division of Oral Pharmacology and Therapeutics, Department of Pharmacology, Medical School, University of Athens, Athens, Greece
    • ,
  • Sophia Anagnostopoulou, MD, DDS, PhD

      Affiliations

    • Associate Professor, Department of Human Anatomy, Medical School, University of Athens, Athens, Greece
    • ,
  • Kostas Danis, MD, DDS, MSc

      Affiliations

    • Regional Epidemiologist, Department of Epidemiology, Health Protection Agency East Midlands, Nottingham City Hospital, Nottingham, UK
    • ,
  • Annete Tachmintzis, MD

      Affiliations

    • Consultant, Department of Anesthesiology, General Hospital of Athens “G. Gennimatas,” Athens, Greece
    • ,
  • George Rallis, MD, DDS, PhD

      Affiliations

    • Senior Hospital Specialist of the Department of Oral & Maxillofacial Surgery, General Hospital of Attica “KAT,” Athens, Greece

References 

  1. Lorurence DR , Benett PN , Brown MJ . From pharmacology to toxicology . In:  Lorurence DR ,  Benett PN ,  Brown MJ editor. Clinical Pharmacology . New York, NY: Churchill Livingstone; 1997;p. 100–101
  2. Friedman LS . Liver, biliary tract and pancreas . In:  Tierney LM ,  McPhee SJ ,  Papadakis MA editor. Current Medical Diagnosis and Treatment . Stamford, CT: Appleton-Lange; 2001;p. 652
  3. Morgan EG . Anaesthesia for patients with liver diseases . In:  Morgan EG editors. Clinical Anesthesiology . New York, NY: Lange Int; 2002;p. 723–735
  4. Butterworth JF , Strichartz GR . Molecular mechanisms of local anesthesia (A review) . Anesthesiology . 1990;86:722
  5. Cassuto J , Wallin G , Hogstrom S . Inhibition of postoperative pain by continuous low dose intravenous infusion of lidocaine . Anesth Analg . 1985;19:18
  6. Kleinman W . Regional anesthesia and pain management . In:  Morgan EG editors. Clinical Anesthesiology . New York, NY: Lange Int; 2002;p. 253
  7. Trujillo TC , Nolan PE . Antiarrythmic agents (drug interactions of clinical significance) . Drug Saf . 2000;23:509
  8. Saranteas T , Mourouzis C , Koumoura F , et al.   Effects of propranolol or paracetamol on lidocane concentrations in serum and tissues . J Oral Maxillofac Surg . 2003;61:604
  9. Popitz-Bergez FA , Leason S , Stichartz GR , et al.   Relation between functional deficit and intraneural local anaesthetic during peripheral nerve block. A study in sciatic nerve . Anesthesiology . 1995;83:583
  10. Doumas BT , Watson WA , Biggs HG . Albumin standards and the measurement of serum albumin with bromocresol green . Clin Chim Acta . 1971;31:87
  11. Tesseromatis C , Fichtl B , Kurz H . Binding of non-steroid anti-inflammatory drugs and warfarin to liver tissue of rabbits in vitro . Eur J Drug Metab Pharmacokin . 1987;12:161
  12. Kurz H , Trunk H , Weitz B . Evaluation of methods to determine protein protein binding of drugs . Arzneim Forsch . 1977;27:1373
  13. Murdoch J , Ritchie N , Greene M . Local anaesthetics . In:  Goodman-Gilman A editors. The Pharmacological Basis of Therapeutics . New York, NY: Pergamon Press; 1990;p. 320
  14. Stoetling KR . Local anesthetics . In:  Stoetling KR editors. Pharmacology and Physiology in Anesthetic Practice . Philadelphia, PA: Lippincott Williams & Wilkins; 1999;p. 158–164
  15. Tetzlaff EJ . Mepivacaine . In:  Tetzlaff EJ editors. Clinical Pharmacology of Local Anesthetics . Boston, MA: Butterworth-Heinemann; 2000;p. 97–102
  16. Galtier M , Briand D , Pinguet F , et al.   Pharmacokinetic parameters of antipyrine in dog after hepatectomy . Biopharm Drug Dispos . 1995;16:669
  17. Jusko W , Gretch M . Plasma and tissue protein binding of drugs in pharmacokinetics . Drug Metab Rev . 1976;5:80
  18. Blassche TF . Protein binding and kinetics of drugs in liver disease . Clin Pharmacokin . 1977;2:32
  19. Azzollini F , Gazzaniga A , Lodola E , et al.   Elimination of chloramphenicol and triamphenicol in subjects with cirrhosis of the liver . Int J Clin Pharmacol Ther Toxicol . 1972;6:130
  20. Tanaka E , Ishikawa A , Misawa S . Changes in caffeine, lidocaine and trimethadione metabolism in carbon tetrachloride-intoxicated rats as assessed by cocktail study . Pharmacol Toxicol . 1994;75:150
  21. Wilkinson GR , Schenker S . Drug disposition and liver disease . Drug Metab Rev . 1975;4:162
  22. Barash P , Cullen B , Soelting KR . Basic principles of clinical pharmacology . In:  Barash P ,  Cullen B ,  Soelting KR editor. Handbook of Clinical Anesthesia . Philadelphia, PA: Lippincott Williams & Wilkins; 2001;p. 104–106
  23. Wilkinson G . Pharmacokinetics . In:  Hardman J ,  Limbird L ,  Goodman-Gilman A editor. The Pharmacological Basis of Therapeutics . New York, NY: McGraw-Hill; 2001;p. 9–10
  24. Jusko W , Gretch M . Plasma and tissue protein binding of drugs in pharmacokinetics . Drug Metab Rev . 1976;5:68
  25. Bickel MH , Steele JW . Binding of basic and acidic drugs to rat tissue subcellular fractions . Chem Biol Interact . 1974;8:151
  26. Saranteas T , Mourouzis C , Dannis C , et al.   Effect of various stress models in lidocaine pharmacokinetics in mandible after masseter injection . J Oral Maxillofac Surg . 2004;62:858

PII: S0278-2391(05)01848-3

doi: 10.1016/j.joms.2005.11.042

Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 6 , Pages 892-895 , June 2006

Article Tools

* Image Usage & Resolution