Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 4 , Pages 576-582 , April 2006

The Efficacy of Postoperative Antibiotic Regimens in the Open Treatment of Mandibular Fractures: A Prospective Randomized Trial

  • Brett A. Miles, DDS, MD

      Affiliations

    • Former Resident, Division of Oral and Maxillofacial Surgery, Parkland Memorial Hospital, University of Texas Southwestern Medical Center, Dallas, TX
    • ,
  • Jason K. Potter, DDS, MD

      Affiliations

    • Former Resident, Department of Oral and Maxillofacial Surgery, Parkland Memorial Hospital, University of Texas Southwestern Medical Center, Dallas, TX
    • ,
  • Edward Ellis III, DDS, MS

      Affiliations

    • Professor and Program Director, Division of Oral and Maxillofacial Surgery, Parkland Memorial Hospital, University of Texas Southwestern Medical Center, Dallas, TX
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Ellis: 5323 Harry Hines Blvd, Dallas, TX 75390-9109

References 

  1. Zallen RD , Curry J . A study of antibiotic usage in compound mandibular fractures . J Oral Surg . 1975;33:431
  2. Greenberg RN , James RB , Marier RL , et al.   Microbiologic and antibiotic aspects of infections in the oral and maxillofacial region . J Oral Surg . 1979;37:873
  3. James RB , Fredrickson C , Kent J . Prospective study of mandibular fractures . J Oral Surg . 1981;39:275
  4. Abubaker A , Rollert M . Postoperative antibiotic prophylaxis in mandibular fractures (A preliminary randomized, double-blind, and placebo-controlled clinical study) . J Oral Maxillofac Surg . 2001;59:1415
  5. Patzakis M . The use of antibiotics in open fractures . Surg Clin North Am . 1975;55:6
  6. Patzakis MJ , Ivler D . Antibiotic and bacteriologic considerations in open fractures . South Med J . 1977;70:1
  7. Patzakis MJ , Harvey JP , Ivler D . The role of antibiotics in the management of open fractures . J Bone Joint Surg . 1974;56-A:532
  8. Bergman BR . Antibiotic prophylaxis in open and closed fractures . Acta Orthop Scand . 1982;53:57
  9. Gustilo RB . Use of antimicrobials in the management of open fractures . Arch Surg . 1979;114:805
  10. Patzakis MJ , Wilkins J , Moore TM . Use of antibiotics in open tibial fractures . Clin Ortho Relat Res . 1983;178:31
  11. Worlock P , Slack R , Harvey L , et al.   The prevention of infection in open fractures (An experimental study of the effect of antibiotic therapy) . J Bone Joint Surg . 1988;70A:9
  12. Aderhold L , Jung H , Frenkel G . Untersuchungen über den wert einer Antibiotika Prophylaxe bei Kiefer-Gesichtsverletzungen. Eine prospective Studie . Dtsch Zahnärztl Z . 1983;38:402
  13. Gerlach KL , Pape H-D . Untersuchungen zur Antibiotikaprophylaxe bei der operativen Behandlung von Unterkieferfrakturen . Dtsch Z Mund Kiefer GesichtsChir . 1988;12:497
  14. Wilkins J , Patzakis M . Choice and duration of antibiotics in open fractures . Orthoped Clin North Am . 1991;22:3
  15. Dellinger EP , Ellis CS , Weaver LD , et al.   Duration of preventive antibiotic administration for open extremity fractures . Arch Surg . 1988;123:333

PII: S0278-2391(06)00005-X

doi: 10.1016/j.joms.2006.01.003

Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 4 , Pages 576-582 , April 2006

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