Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 7 , Pages 1066-1074 , July 2006

The Relationship Between Temporomandibular Joint Synovitis and Adhesions: Pathogenic Mechanisms and Clinical Implications for Surgical Management

  • Howard A. Israel, DDS

      Affiliations

    • Professor of Clinical Surgery, Department of Surgery, Cornell University, New York, NY
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Israel: Cornell University Weill Medical College, 525 East 68th Street, Suite F2132, New York, NY 10021
    • ,
  • Claude-Jean Langevin, DMD, MD

      Affiliations

    • Formerly, Chief Resident, Oral and Maxillofacial Surgery, New York Presbyterian Hospital–Weill Cornell Medical Center, New York, NY
    • ,
  • Michael D. Singer, DMD

      Affiliations

    • Formerly, Chief Resident, Oral and Maxillofacial Surgery, New York Presbyterian Hospital–Weill Cornell Medical Center, New York, NY
    • ,
  • David A. Behrman, DMD

      Affiliations

    • Chief, Division of Dentistry and Oral and Maxillofacial Surgery, Department of Surgery, Cornell University, New York, NY

References 

  1. Emshoff R , Rudisch A . Are internal derangement and osteoarthrosis linked to changes in clinical outcome measures of arthrocentesis of the temporomandibular joint? . J Oral Maxillofac Surg . 2003;61:1162
  2. Katzberg RW , Westesson PL , Tallents RH , et al.   Anatomic disorders of the temporomandibular joint disc in asymptomatic subjects . J Oral Maxillofac Surg . 1996;54:147
  3. Moore JB . Coronal and sagittal TMJ meniscus position in asymptomatic subjects by MRI . J Oral Maxillofac Surg . 1989;47:75
  4. Kircos LT , Ortendahl DA , Mark AS , et al.   Magnetic resonance imaging of the TMJ disc in asymptomatic volunteers . J Oral Maxillofac Surg . 1987;45:852
  5. Trumpy IG , Lyberg T . Surgical treatment of internal derangement of the temporomandibular joint (Long-term evaluation of three techniques) . J Oral Maxillofac Surg . 1995;53:746
  6. Quinn JH , Bazan NG . Identification of prostaglandin E2 and leukotriene B4 in the synovial fluid of painful, dysfunctional temporomandibular joints . J Oral Maxillofac Surg . 1990;48:968
  7. Shafer DM , Assael L , White LB , et al.   Tumor necrosis factor alpha as a biochemical marker of pain and outcome in temporomandibular joints with internal derangements . J Oral Maxillofac Surg . 1994;52:786
  8. Kopp S . Neuroendocrine, immune and local responses related to temporomandibular disorders . J Orofac Pain . 2001;15:9
  9. Ratcliffe A , Israel HA . Proteoglycan components of articular cartilage in synovial fluids as potential markers of osteoarthritis of the temporomandibular joint . In:  Sessle BJ ,  Bryant PS ,  Dionne RA editor. Temporomandibular Disorders and Related Pain Conditions, Progress in Pain Research and Management . Vol 4: Seattle, WA: IASP Press; 1995;p. 141–150
  10. Israel H , Diamond B , Saed-Nejad F , et al.   Correlation between arthroscopic diagnosis of osteoarthritis and synovitis of the human temporomandibular joint and keratan sulfate levels in the synovial fluid . J Oral Maxillofac Surg . 1997;55:210
  11. Kubota E , Imamura H , Kubota T , et al.   Interleukin 1 beta and stromelysin (mmp3) activity of synovial fluid as possible markers of osteoarthritis in the temporomandibular joint . J Oral Maxillofac Surg . 1997;55:20
  12. Kubota E , Kubota T , Matsumoto J , et al.   Synovial fluid cytokines and proteinases as markers of temporomandibular joint disease . J Oral Maxillofac Surg . 1998;56:192
  13. Israel H , Diamond B , Saed-Nejad F , et al.   Osteoarthritis and synovitis as major pathoses of the tempromandibular joint (comparison of clinical diagnosis and arthroscopic morphology) . J Oral Maxillofac Surg . 1998;56:1023
  14. Murakami K , Segami N , Fujimura K , et al.   Correlation between pain and synovitis in patients with internal derangement of the temporomandibular joint . J Oral Maxillofac Surg . 1992;50:705
  15. Nitzan DW , Kreiner B , Zelster R . TMJ lubrication system (Its effect on the joint function dysfunction and treatment approach) . Compend Contin Educ Dent . 2004;25:437
  16. Murakami K , Ito K . Arthroscopy of the temporomandibular joint . In:  Watanabe M editors. Arthroscopy of Small Joints . Tokyo, Japan/New York, NY: Igaku Shion; 1986;p. 128–139
  17. Israel HA . Temporomandibular joint arthroscopy . In:  Peterson L editors. Principles of Oral and Maxillofacial Surgery . Philadelphia, PA: Lippincott; 1992;p. 2015–2042
  18. Senga K , Mizutani H , Kobayashi M , et al.   Ultrastructural study on adhesions in internal derangement of the temporomandibular joint . J Oral Maxillofac Surg . 1999;57:165
  19. Dijkgraaf LC , DeBont LGM , Boering G , et al.   The structure, biochemistry and metabolism of osteoarthritic cartilage (A review of the literature) . J Oral Maxillofac Surg . 1995;53:1182
  20. Milam SB , Schmitz JP . Molecular biology of temporomandibular joint disorders (proposed mechanisms of disease) . J Oral Maxillofacial Surg . 1995;53:1448
  21. Dijkgraff L , Zardeneta G , Cordewener F , et al.   Crosslinking of fibrinogen and fibronectin by free radicals (A possible initial step in adhesion formation in osteoarthritis of the temporomandibular joint) . J Oral Maxillofacial Surg . 2003;61:101
  22. Yoshida M , Funasaki H , Saito M , et al.   Pathologic gene expression in adhesive subacromial bursae of human shoulder . Clin Orthop Relat Res . 2003;412:57
  23. Fujisawa T , Kuboki T , Kasai T , et al.   A repetitive, steady mouth opening induced an osteoarthritis-like lesion in the rabbit temporomandibular joint . J Dent Res . 2003;82:731
  24. Yamaza T , Masuda KF , Atsuta I , et al.   Oxidative stress-induced DNA damage in the synovial cells of the tempromandibular joint in the rat . J Dent Res . 2004;83:619
  25. Muto T , Kawakami J , Kanazawa M , et al.   Histologic study of synovitis induced by trauma to the rat temporomandibular joint . Oral Surg Oral Med Oral Pathol Oral Radiol Endod . 1998;86:534
  26. Israel H , Diamond B , Saed-Nejad F , et al.   The relationship between prafunctional masticatory activity and arthroscopically diagnosed temporomandibular joint pathology . J Oral Maxillofac Surg . 1999;57:1034
  27. Ratcliffe A , Israel H , Saed-Nejad F , et al.   Proteoglycans in the synovial fluid of the temporomandibular joint as an indicator of changes in cartilage metabolism during primary and secondary osteoarthritis . J Oral Maxillofac Surg . 1998;56:204
  28. Shibata T , Murakami KI , Kubota E , et al.   Glycosaminoglycan components in temporomandibular joint synovial fluid as markers of joint pathology . J Oral Maxillofac Surg . 1998;56:209
  29. Salter RB . The biologic concept of continuous passive motion of synovial joints. The first 18 years of basic research and its clinical application . Clin Orthop Relat Res . 1989;242:12
  30. Akeson WH , Amiel D , Abel MF , et al.   Effects of immobilization on joints . Clin Orthop Relat Res . 1987;219:28
  31. Trudel G , Jabi M , Uhthoff HK . Localized and adaptive syonviocyte proliferation characteristics in rat knee joint contractures secondary to immobility . Arch Phys Med Rehabil . 2003;84:1350
  32. Stegenga B , DeBont LGM , Boering G . Osteoarthrosis as the cause of craniomandibular pain and dysfunction (A unifying concept) . J Oral Maxillofac Surg . 1989;47:249
  33. Stegenga B , DeBont LGM , Boering G , et al.   Tissue responses to degenerative changes in the temporomandibular joint (A review) . J Oral Maxillofac Surg . 1991;49:1079
  34. Stegenga B . Osteoarthritis of the temporomandibular joint organ and its relationship to disc displacement . J Orofac Pain . 2001;15:193
  35. Schiffman EL , Anderson GC , Fricton JR , et al.   The relationship between level of mandibular pain and dysfunction and stage of temporomandibular joint internal derangement . J Dent Res . 1992;71:1812
  36. Orbach S . Meniscal disorders . N Y State Dent J . 1996;62:24
  37. Romanelli GG , Harper R , Mock D , et al.   Evaluation of temporomandibular joint internal derangement . J Orofac Pain . 1993;7:254
  38. Ribeiro RF , Tallents RH , Katzberg RW , et al.   The prevalence of disc displacment in symptomatic and asymptomatic volunteers aged 6 to 25 years . J Orofac Pain . 1997;11:37
  39. Dolwick MF . Intra-articular disc displacement. Part I: Its questionable role in temporomandibular joint pathology . J Oral Maxillofac Surg . 1995;53:1069
  40. Luder HU . Articular degeneration and remodeling in human temporomandibular joints with normal and abnormal disc position . J Orofac Pain . 1993;7:391
  41. Yura S , Totsuka Y , Yoshikawa T , et al.   Can arthrocentesis release intracapsular adhesions? Arthroscopic findings before and after irrigation under sufficient hydraulic pressure . J Oral Maxillofac Surg . 2003;61:1253

PII: S0278-2391(06)00376-4

doi: 10.1016/j.joms.2006.03.012

Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 7 , Pages 1066-1074 , July 2006

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