Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 7 , Pages 1059-1065 , July 2006

Impact of Topical Minocycline With Third Molar Surgery on Clinical Recovery and Health-Related Quality of Life Outcomes

  • Mary F. Stavropoulos, DDS

      Affiliations

    • Associate Professor, Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Florida, Gainesville, FL
    • ,
  • Daniel A. Shugars, DDS, PhD, MPH

      Affiliations

    • Professor, Department of Operative Dentistry, School of Dentistry, University of North Carolina, Chapel Hill, NC
    • ,
  • Ceib Phillips, MPH, PhD

      Affiliations

    • Professor, Department of Orthodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC
    • ,
  • Shawn M. Conrad, DDS

      Affiliations

    • Clinical Assistant Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, University of North Carolina, Chapel Hill, NC, and Community Practice Oral and Maxillofacial Surgery, Wilmington, NC
    • ,
  • Phillip T. Fleuchaus, DDS, MSD

      Affiliations

    • Private Practice, Community Practice Oral and Maxillofacial Surgery, Daytona Beach, FL
    • ,
  • Raymond P. White Jr, DDS, PhD

      Affiliations

    • Dalton L. McMichael Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, University of North Carolina, Chapel Hill, NC
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr White: School of Dentistry, Department of Oral and Maxillofacial Surgery, University of North Carolina, CB 7450, Chapel Hill, NC 27599-7450

References 

  1. White RP , Shugars DA , Shafer DM , et al.   Clinical and health related quality of life outcomes during recovery after third molar surgery . J Oral Maxillofac Surg . 2003;61:535
  2. Goldberg MH , Nemarich AN , Marco WP . Complications after mandibular third molar surgery (A statistical analysis of 500 consecutive procedures in private practice) . J Am Dent Assoc . 1985;111:277
  3. Osborn T , Fredrickson B , Small I , et al.   A prospective study of complications related to mandibular third molar surgery . J Oral Maxillofac Surg . 1985;43:767
  4. Bruce RA , Fredrickson GC , Small GS . Age of patients and morbidity associated with third molar surgery . J Am Dent Assoc . 1980;101:240
  5. Piecuch JF , Arzadon J , Lieblich SE . Prophylactic antibiotics for third molar surgery (A supportive opinion) . J Oral Maxillofac Surg . 1995;53:53
  6. Phillips C , White RP , Shugars D , et al.   Risk factors associated with prolonged recovery and delayed clinical healing after third molar surgery . J Oral Maxillofac Surg . 2003;61:1436
  7. Ruvo A , Shugars DA , White RP , et al.   Delayed clinical recovery and health related quality of life outcomes after third molar surgery . J Oral Maxillofac Surg . 2005;63:929
  8. Foy SP , Shugars D , Phillips C , et al.   Outcomes following third molar surgery with intravenous antibiotics in patients at risk for delayed recovery . J Oral Maxillofac Surg . 2004;62:15
  9. Alexander RE . Dental extraction wound management (A case against medicating postextraction sockets) . J Oral Maxillofac Surg . 2000;58:538
  10. Blakey GH , White RP , Offenbacher S , et al.   Clinical/biological outcomes of treatment for pericoronitis . J Oral Maxillofac Surg . 1996;54:1150
  11. Dahlen G . Microbiology and treatment of dental abscesses and periodontal-endodontic lesions . Periodontol 2000 . 2002;28:206
  12. Williams RC , Paquette DW , Offenbacher S , et al.   Treatment of periodontitis by local administration of minocycline microspheres (A controlled trial) . J Periodontol . 2001;72:1535
  13. Conrad SM , Blakey GH , Shugars DA , et al.   Patients’ perception of recovery following third molar surgery . J Oral Maxillofac Surg . 1999;57:1288
  14. Socransky SS , Haffajee AD , Cugini MA , et al.   Microbial complexes in subgingival plaque . J Clin Periodontol . 1998;25:134
  15. Vezeau PJ . Dental extraction wound management (medicating postextraction sockets) . J Oral Maxillofac Surg . 2000;58:531
  16. Moore JW , Brekke JH . Foreign body giant cell reaction related to placement of tetracycline-treated polylactic acid (report of 18 cases) . J Oral Maxillofac Surg . 1990;48:808
  17. Zuniga JR , Leist JC . Topical tetracycline-induced neuritis (a case report) . J Oral Maxillofac Surg . 1995;53:196
  18. Leist JC , Zuniga JR , Chen N , et al.   Experimental topical tetracycline-induced neuritis in the rat . J Oral Maxillofac Surg . 1995;53:427
  19. Salvi GE , Lawrence HP , Offenbacher S , et al.   Influence of risk factors on the pathogenesis of periodontitis . Periodontol 2000 . 1997;14:173
  20. Hugoson A , Kugelberg CF . The prevalence of third molars in a Swedish population. An epidemiological study . Community Dent Health . 1987;5:121

 This study was supported and funded by the Dental Foundation of North Carolina, the Oral and Maxillofacial Surgery Foundation, and the American Association of Oral and Maxillofacial Surgeons.

PII: S0278-2391(06)00381-8

doi: 10.1016/j.joms.2006.03.007

Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 7 , Pages 1059-1065 , July 2006

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