Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 10 , Pages 1498-1505 , October 2006

Bone Regeneration in Mandibular Distraction Osteogenesis Combined With Compression Stimulation

This study was presented at the 84th Annual Meeting of American Association of Oral and Maxillofacial Surgeons, 2002, Chicago, IL.

  • Uk-Kyu Kim, DDS, PhD

      Affiliations

    • Associate Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University, Busan, South Korea.
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Kim: Department of Oral and Maxillofacial Surgery, Pusan National University Hospital, Amidong 1-10, Seogu, Busan, South Korea
    • ,
  • In-Kyo Chung, DDS, PhD

      Affiliations

    • Professor and Chair, Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University, Busan, South Korea.
    • ,
  • Kwang-Ho Lee, DDS, MS

      Affiliations

    • Resident, Department of Oral and Maxillofacial Surgery, Dong-A University Medical Center, Busan, South Korea.
    • ,
  • James Q. Swift, DDS

      Affiliations

    • Professor and Director, Division of Oral and Maxillofacial Surgery, Department of Oral Diagnostic & Surgical Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN.
    • ,
  • Wook-Jin Seong, DDS, MS

      Affiliations

    • Associate Clinical Specialist, Division of Prosthodontics, Department of Restorative Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN.
    • ,
  • Ching-Chang Ko, DDS, PhD

      Affiliations

    • Assistant Professor, Department of Oral Science, Minnesota Dental Research Center, School of Dentistry, University of Minnesota, Minneapolis, MN.

References 

  1. Mikhail LS , Cherkashin AM , Cope JB . Distraction osteogenesis: History and biologic basis of new bone formation . In:  Lynch SE ,  Genco RJ ,  Mark RE editor. Tissue Engineering: Applications in Maxillofacial Surgery and Periodontics . Ed 2. Carol Stream, IL: Quintessence; 1998;p. 130
  2. Snyder CC , Levine GA , Swanson HM , et al.   Mandibular lengthening by gradual distraction . Plast Reconstr Surg . 1973;51:506
  3. McCarthy JG , Schreiber J , Karp N , et al.   Lengthening of the human mandible by gradual distraction . Plast Reconstr Surg . 1992;89:1
  4. Davies J , Turner S , Sandy JR . Distraction osteogenesis–A review . Br Dent J . 1998;185:462
  5. Molina F , Ortiz MF . Mandibular elongation and remodeling by distraction: A farewell to major osteotomies . Plast Reconstr Surg . 1995;96:825
  6. Block MS , Chang A , Crawford C . Mandibular alveolar ridge augmentation in the dog using distraction osteogenesis . J Oral Maxillofac Surg . 1996;54:309
  7. Costantino PD , Shybut G , Schreiber JS , et al.   Segmental mandibular regeneration by distraction osteogenesis . Arch Otolaryngol Head Neck Surg . 1990;116:535
  8. Klein C , Howaldt HP . Correction of mandibular hypoplasia by means of bidirectional callus distraction . J Craniofac Surg . 1996;7:258
  9. Karp NS , Thorne CHM , McCarthy JG , et al.   Bone lengthening in the craniofacial skeleton . Ann Plast Surg . 1990;24:231
  10. Ilizarov GA . Basic principle of transosseous compression and distraction osteogenesis . Ortop Travmatol Protez . 1971;32:7
  11. Klotch DW , Ganey TM , Slater-Hasse A , et al.   Assessment of bone formation during osteogenesis (A canine model) . Otolaryngol Head Neck Surg . 1995;112:291
  12. Ilizarov GA . Clinical application of tension-stress effect for limb lengthening . Clin Orthop . 1990;250:8
  13. Fischgrund J , Paley D , Suter C . Variables affecting time to bone healing during limb lengthening . Clin Orthop . 1994;301:31
  14. Greenwald JA , Luchs JS , Mehrara BJ , et al.   “Pumping the regenerate”: A evaluation of oscillating distraction osteogenesis in the rodent mandible . Ann Plast Surg . 2000;4:516
  15. Raschke MJ , Bail H , Windhagen HJ , et al.   Recombinant growth hormone accelerates bone regenerate consolidation in distraction osteogenesis . Bone . 1999;24:81
  16. Pepper JR , Herbert MA , Anderson JR , et al.   Effect of capacitive coupled electrical stimulation on regenerate bone . J Orthop Res . 1996;14:296
  17. Mizumoto Y , Moseley T , Timothy BS , et al.   Acceleration of regenerate ossification during distraction osteogenesis with recombinant human bone morphogenetic protein-7 . J Bone Joint Surg Am . 2003;85:124
  18. Mofid MM , Inoue N , Atabey A , et al.   Callus stimulation in distraction osteogenesis . Plast Reconstr Surg . 2002;109:1621
  19. Pacicca DM , Moore DC , Ehrlich MG , et al.   Physiologic weight-bearing and consolidation of new bone in rat model of distraction osteogenesis . J Pediatr Orthop . 2002;22:652
  20. McCarthy J , Hopper R , Hollier L , et al.   Molding of the regenerate in mandibular distraction: Clinical experience . Plast Reconstr Surg . 2003;112:1239
  21. Kunz C , Hammer B , Prein J . Manipulation of callus after linear distraction: A “lifeboat” or an alternative to multivectorial distraction osteogenesis of the mandible? . Plast Reconstr Surg . 2000;105:674
  22. Vollmer D , Meyer U , Piffko J , et al.   Experimental and finite element study of a human mandible . J Craniofacial Surg . 2000;28:91
  23. Meyer U , Wiesmann HP , Kruse-Losler B , et al.   Strain-related bone remodeling in distraction osteogenesis of the mandible . Plast Reconstr Surg . 1999;103:800
  24. Mosley JR , March BM , Lynch J , et al.   Strain magnitude related change in which bone architecture in growing rats . Bone . 1997;20:191
  25. Chang MC , Ko CC , Liu CC , et al.   Elasticity of alveolar bone near dental implant-bone interfaces after one month’s healing . J Biomechanics . 2003;36:1209
  26. McCarthy JG , Stelnicki EJ , Mehrara BJ , et al.   Distraction osteogenesis of the craniofacial skeleton . Plast Reconstr Surg . 2001;107:1812
  27. Aronson J , Shen XC , Skinner RA , et al.   Rat model of distraction osteogenesis . J Orthop Res . 1997;15:221
  28. McCarthy JG , Williams JK , Grayson BH , et al.   Controlled multiple distraction of the mandible: Device development and clinical application . J Craniofac Surg . 1998;9:322
  29. Kassis B , Glorion C , Tabib W , et al.   Callus response to micromovement after elongation in the rabbit . J Pediatr Orthop . 1996;16:480
  30. Codivilla A . On the means of lengthening in the lower limbs, the muscles, and tissues which are shortened through deformity . Am J Orthop Surg . 1905;2:353; (cited from a reprint of the original article under the title “The Classic” in Clin Orthop 301:4, 1994)
  31. Ilizarov GA . The tension-stress effect on the genesis and growth of tissue: Part I (The influence of stability of fixation and soft-tissue preservation) . Clin Orthop . 1989;238:249
  32. Ilizarov GA . The tension-stress effect on the genesis and growth of tissue: Part II The influence of the rate and frequency of distraction . Clin Orthop . 1989;239:263
  33. Peltomaki T , Grayson BH , Vendittelli BL , et al.   Moulding of the generate to control open bite during mandibular distraction osteogenesis . Eur J Orthod . 2002;24:639
  34. Castello JR , Olaso AS , Chao JJ , et al.   Craniofacial shortening by contraction osteogenesis: An experimental model . Plast Reconstr Surg . 2000;105:617; discussion 626
  35. Aro HT , Kelly PJ , Lewallen DG , et al.   The effects of physiologic dynamic compression on bone healing under external fixation . Clin Orthopaed Relat Res . 1990;256:260
  36. Van’t Veen SJ , Hagen JW , van Ginkel FC , et al.   Intermittent compression stimulates cartilage mineralization . Bone . 1995;17:461
  37. Burger EH , Klein-Nulend J , Veldhuijzen JP . Mechanical stress and osteogenesis in vitro . J Bone Miner Res . 1992;7(suppl 2):S397
  38. Yasui N , Sato M , Ochi T , et al.   Three models of ossification during distraction osteogenesis in the rat . J Bone Joint Surg . 1997;79B:824
  39. Luchs JS , Steinicki EJ , Rowe NM , et al.   Molding of the regenerate in mandibular distraction: Part 1: Laboratory study . J Craniofac Surg . 2002;13:205
  40. Kojimoto H , Yasui N , Goto T , et al.   Bone lengthening in rabbits by callus distraction (The role of the periosteum and endosteum) . J Bone Joint Surg . 1988;70B:543
  41. Paccione MF , Mehrara BJ , Warren SM , et al.   Rat mandibular distraction osteogenesis: Latency, rate, and rhythm determine the adaptive response . J Craniofac Surg . 2001;12:175
  42. Karaharju-Suvanto T , Karaharju EO , Ranta R . Mandibular distraction (An experimental study on sheep) . J Craniomaxillofac Surg . 1990;18:280
  43. Aida T , Yoshioka I , Tominaga K , et al.   Effects of latency period in a rabbit mandibular distraction osteogenesis . Int J Oral Maxillofac Surg . 2003;32:54
  44. Thurmuller P , Troulis MJ , Rosenberg A , et al.   Changes in the condyle and disc in response to distraction osteogenesis of the minipig mandible . J Oral Maxillofac Surg . 2002;60:1327
  45. Kassis B , Glorion C , Tabib W , et al.   Callus response to micromovement during elongation in the rabbit . J Pediatr Orthopaed . 1998;18:586
  46. Meyer U , Wiesmann HP , Kruse-Losler B , et al.   Strain-related bone remodeling in distraction osteogenesis of the mandible . Plast Reconstr Surg . 1999;103:800
  47. Karp NS , McCarthy JG , Schreiber JS , et al.   Membrane bone lengthening: A serial histological study . Ann Plast Surg . 1992;29:2
  48. Smith SW , Sachdeva RC , Cope JB . Evaluation of the consolidation period during osteodistraction using computed tomography . Am J Orthod Dentofacial Orthop . 1999;116:254
  49. Rowe NM , Mehrara BJ , Dudziak ME , et al.   Rat mandibular distraction osteogenesis: Part I (Histologic and radiographic analysis) . Plast Reconstr Surg . 1998;102:2022
  50. Babak JM , Norman MR . Rat mandibular distraction osteogenesis: II (Molecular analysis of transforming growth factor beta-1 and osteocalcin gene expression) . Plast Reconstr Surg . 1999;103:536
  51. Warren SM , Mehrara BJ , Steinbrech DS , et al.   Rat mandibular distraction osteogenesis: Part III (Gradual distraction versus acute lengthening) . Plast Reconstr Surg . 2001;107:441
  52. Moalli MR , Caldwell NJ , Patil PV , et al.   An in vivo model for investigation of mechanical signal transduction in trabecular bone . J Bone Miner Res . 2000;15:1346
  53. Inaoka T , Lean JM , Bessho T , et al.   Sequential analysis of gene expression after an osteogenic stimulus: c-fos expression is induced in osteocytes . Biochem Biophys Res Commun . 1995;217:264
  54. McCabe LR , Kockx M , Lian J , et al.   Selective expression of fos- and jun-related genes during osteoblast proliferation and differentiation . Exp Cell Res . 1995;218:255
  55. Towler DA , Rutledge SJ , Rodan GA , et al.   Msa-2/Hox 8.1: A transcriptional regulator of the rat osteocalcin promoter . Mol Endocrinol . 1994;8:1484
  56. Harada S , Wesolowski G , Suva LG , et al.   The role of zif-268 and insulin-like growth factor-I in prostaglandin stimulation of growth in osteoblastic cells . J Bone Miner Res . 1991;6(suppl 1):A220
  57. Massague J . TGF-β signaling: Receptors, transducers, and mad proteins . Cell . 1996;85:947
  58. Wozney JM , Rosen V , Celeste AJ , et al.   Novel regulators of bone formation: Molecular clones and activities . Science . 1988;242:1528
  59. Yao K , Todescan R , Sodek J . Temporal changes in matrix protein synthesis and mRNA expression during mineralized tissue formation by adult rat bone marrow cells in culture . J Bone Miner Res . 1994;9:231
  60. Komuro Y , Takato T , Harii K , et al.   The histologic analysis of distraction osteogenesis of the mandible in rabbits . Plast Reconstr Surg . 1993;94:152

PII: S0278-2391(06)00393-4

doi: 10.1016/j.joms.2006.03.028

Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 10 , Pages 1498-1505 , October 2006

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