Adenoid Cystic Carcinoma and Mucoepidermoid Carcinoma of the Maxillary Sinus: Report of a 44-Year Experience of 25 Cases From a Single Institution
Purpose
The aim of this study was to analyze the clinicopathologic characteristics of all cases of adenoid cystic carcinoma (ACC) and mucoepidermoid carcinoma (MEC) arising in the maxillary sinuses treated in a single institution.
Patients and Methods
From 1953 to 1997, 18 ACCs and 7 MECs from the maxillary sinus were studied. Clinical data were obtained from the medical records and microscopic slides were reviewed.
Results
Mean age was 45.9 years (range, 13 to 77 years) and TNM staging revealed 88.9% of ACCs at advanced clinical stages, while 57.1% of the MECs were initial clinical stages. Surgery combined with radiotherapy was the most common treatment. Follow-up showed 88.8% of ACC patients died from the tumor, while 42.8% of patients with MEC are alive without disease.
Conclusion
Maxillary sinus ACC and MEC are uncommon tumors and a patient’s prognosis depends on the clinical stage and histologic type; MEC has shown a better outcome.
⁎Professor, Oral Pathology and Semiology, School of Dentistry of Piracicaba, State University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
†Professor, Oral Pathology, School of Dentistry, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil.
‡Titular Professor, Oral Pathology and Semiology, School of Dentistry of Piracicaba, State University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
§Head, Oral Pathology and Semiology, School of Dentistry of Piracicaba, State University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.
¶Head, Department of Head and Neck Surgery and Otorhinolaryngology, AC Camargo Cancer Hospital, São Paulo, Brazil.
Address correspondence and reprint requests to Dr Perez: Faculdade de Odontologia de Piracicaba, Av Limeira, 901, Areão, CEP 13414-018, Piracicaba/SP, Brazil
This work was supported by The State of Sao Paulo Research Foundation (FAPESP) and National Council for Scientific and Technological Development (CNPq), Brazil.
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