Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 4 , Pages 675-679 , April 2007

Surgical Management of Squamous Cell Carcinoma of the Lip: Analysis of a 10-Year Experience in 223 Patients

  • Miroslav Vukadinovic, MD, DDS, PhD

      Affiliations

    • Professor, Clinic for the Maxillofacial Surgery, Faculty of Dentistry, University of Belgrade, Belgrade, Serbia.
  • ,
  • Zoran Jezdic, DDS

      Affiliations

    • Assistant Clinical Professor, Clinic for the Maxillofacial Surgery, Faculty of Dentistry, University of Belgrade, Belgrade, Serbia.
  • ,
  • Milan Petrovic, MD

      Affiliations

    • Clinic for the Maxillofacial Surgery, Faculty of Dentistry, University of Belgrade, Belgrade, Serbia.
  • ,
  • Ljiljana M. Medenica, MD, PhD

      Affiliations

    • Professor, Institute of Dermatology and Venereology, Department of Dermatology and Venereology, School of Medicine, University of Belgrade, Belgrade, Serbia.
  • ,
  • Marko Lens, MD, PhD

      Affiliations

    • Senior Lecturer, Genetic Epidemiology Unit, King’s College, St Thomas’ Hospital, London, UK.
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Lens: Genetic Epidemiology Unit, King’s College, St Thomas’ Hospital, Lambeth Palace Road, London SE1 7EH, UK

References 

  1. Zitsch RP, Park CW, Renner GJ, et al. Outcome analysis for lip carcinoma. Otolaryngol Head Neck Surg. 1995;113:589
  2. Sykes AJ, Allan E, Irwin C. Squamous cell carcinoma of the lip: The role of electron treatment. Clin Oncol (R Coll Radiol). 1996;8:384
  3. de Visscher JG, van der Waal I. Epidemiology of cancer of the lip in The Netherlands. Oral Oncol. 1998;34:421
  4. Moretti A, Zingariello P, Chiri ZM, et al. Surgical treatment of malignant lip tumors (Personal experience). G Chir. 2003;24:341
  5. Chen J, Katz RV, Krutchkoff DJ, et al. Lip cancer (Incidence trends in Connecticut, 1935-1985). Cancer. 1992;70:2025
  6. de Visscher JG, Grond AJ, Otter R, et al. Lip carcinoma (A review). Ned Tijdschr Tandheelkd. 2002;109:391
  7. Zitsch RP. Carcinoma of the lip. Otolaryngol Clin North Am. 1993;26:265
  8. Coppit GL, Lin DT, Burkey BB. Current concepts in lip reconstruction. Curr Opin Otolaryngol Head Neck Surg. 2004;12:281
  9. Campbell JP. Surgical management of lip carcinoma. J Oral Maxillofac Surg. 1998;56:955
  10. Baker SR. Regional flaps in facial reconstruction. Otolaryngol Clin North Am. 1990;23:925
  11. Karapandzic M. Reconstruction of lip defects by local arterial flaps. Br J Plast Surg. 1974;27:93
  12. Luce EA, Goldberg DP. Oncologic and reconstructive considerations in nonmelanotic skin and lip cancers. Surg Oncol Clin North Am. 1996;5:751
  13. de Visscher JG, Gooris PJ, Vermey A, et al. Surgical margins for resection of squamous cell carcinoma of the lower lip. Int J Oral Maxillofac Surg. 2002;31:154
  14. Holmkvist KA, Roenigk RK. Squamous cell carcinoma of the lip treated with Mohs micrographic surgery: Outcome at 5 years. J Am Acad Dermatol. 1998;38:960
  15. Zide MF, Adnot J. Lower lip cancer: Mohs micrographic surgery and reconstruction as a multidisciplinary effort. J Oral Maxillofac Surg. 1997;55:818
  16. O’Quinn RP, Stasko T. Repair of the lower lip after Mohs micrographic surgery. Dermatol Surg. 2001;27:845
  17. Cerezo L, Liu FF, Tsang R, et al. Squamous cell carcinoma of the lip: Analysis of the Princess Margaret Hospital experience. Radiother Oncol. 1993;28:142
  18. Babington S, Veness MJ, Cakir B, et al. Squamous cell carcinoma of the lip: Is there a role for adjuvant radiotherapy in improving local control following incomplete or inadequate excision?. ANZ J Surg. 2003;73:621
  19. Veness MJ, Ong C, Cakir B, et al. Squamous cell carcinoma of the lip (Patterns of relapse and outcome: Reporting the Westmead Hospital experience, 1980-1997). Australas Radiol. 2001;45:195
  20. Bucur A, Stefanescu L. Management of patients with squamous cell carcinoma of the lower lip and N0-neck. J Craniomaxillofac Surg. 2004;32:16
  21. Zitsch RP, Lee BW, Smith RB. Cervical lymph node metastases and squamous cell carcinoma of the lip. Head Neck. 1999;21:447
  22. Vartanian JG, Carvalho AL, de Araujo Filho MJ, et al. Predictive factors and distribution of lymph node metastasis in lip cancer patients and their implications on the treatment of the neck. Oral Oncol. 2004;40:223
  23. Awde JD, Kogon SL, Morin RJ. Lip cancer: A review. J Can Dent Assoc. 1996;62:634
  24. Ochsenius G, Ormeno A, Godoy L, et al. A retrospective study of 232 cases of lip cancer and pre cancer in Chilean patients (Clinical-histological correlation). Rev Med Chil. 2003;131:60
  25. Palme CE, Gullane PJ, Gilbert RW. Current treatment options in squamous cell carcinoma of the oral cavity. Surg Oncol Clin North Am. 2004;13:47

PII: S0278-2391(06)01356-5

doi: 10.1016/j.joms.2006.03.054

Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 4 , Pages 675-679 , April 2007