Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 3 , Pages 434-438 , March 2007

Management of Extensive Osteoradionecrosis of the Mandible With Radical Resection and Immediate Microvascular Reconstruction

  • Marcos Martins Curi, PhD

      Affiliations

    • Chairman, Department of Stomatology, Hospital Santa Catarina, Sao Paulo, Brazil.
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Curi: Hospital Santa Catarina, Oncology, Rua Vieira de Moraes 45-121, Campo Belo, 04617-010 Sao Paulo, SP, Brazil
    • ,
  • Marcelo Oliveira dos Santos, MD

      Affiliations

    • Chairman, Department of Clinical Oncology, Hospital Santa Catarina, Sao Paulo, Brazil.
    • ,
  • Olavo Feher, MD

      Affiliations

    • Professor, Department of Clinical Oncology, Hospital Santa Catarina, Sao Paulo, Brazil.
    • ,
  • José Carlos Marques Faria, MD

      Affiliations

    • Assistant Professor, Department of Head and Neck Surgery, Hospital A.C. Camargo, Sao Paulo, Brazil.
    • ,
  • Mŏnica Lúcia Rodrigues, MD

      Affiliations

    • Assistant Professor, Department of Head and Neck Surgery, Hospital A.C. Camargo, Sao Paulo, Brazil.
    • ,
  • Luiz Paulo Kowalski, MD, PhD

      Affiliations

    • Chairman, Department of Head and Neck Surgery, Hospital A.C. Camargo, Sao Paulo, Brazil.

References 

  1. Curi MM, Dib LL. Osteoradionecrosis of the jaws: A retrospective study of the background factors and treatment in 104 cases. J Oral Maxillofac Surg. 1997;55:540
  2. Curi MM, Dib LL, Kowalski LP. Management of refractory osteoradionecrosis of the jaws with surgery and adjunctive hyperbaric oxygen therapy. Int J Oral Maxillofac Surg. 2000;29:430
  3. Kluth EV, Jain PR, Stuchell RN, et al. A study factor contributing to the development of osteoradionecrosis of the jaws. J Prosthet Dent. 1988;59:194
  4. Koka VN, Lusinchi A, Roland J, et al. Osteoradionecrosis of the mandible: Study of 104 cases treated by hemimandibulectomy. J Laryngol Otol. 1990;104:305
  5. Epstein JB, Wong FLW, Stevenson-Moore P. Osteoradionecrosis: Clinical experience and a proposal for classification. J Oral Maxillofac Surg. 1987;45:104
  6. Marx RE. Osteoradionecrosis: A new concept of its pathophysiology. J Oral Maxillofac Surg. 1983;41:283
  7. Wong JK, Wood RE, Mclean M. Conservative management of osteoradionecrosis. Oral Surg Oral Med Oral Pathol. 1997;84:16
  8. Aitasalo K, Niinikoski J, Grenman R, et al. A modified protocol for early treatment of osteomyelitis and osteoradionecrosis of the mandible. Head Neck. 1998;20:411
  9. Coleman JJ, Wooden WA. Mandibular reconstruction with composite microvascular tissue transfer. Am J Surg. 1990;160:390
  10. Hao SP, Chen HC, Wei FC, et al. Systematic management of osteoradionecrosis in the head and neck. Laryngoscope. 1999;109:1324
  11. Marx RE, Johnson RP. Studies in the radiobiology of osteoradionecrosis and their clinical significance. Oral Surg Oral Med Oral Pathol. 1987;64:379
  12. Merkesteyn JPR, Bakker DJ, Borgmeijer-Hoelen AMMJ. Hyperbaric oxygen treatment of osteoradionecrosis of the mandible (Experience in 29 patients). Oral Surg Oral Med Oral Pathol. 1995;80:12
  13. Neovius EB, Lind MG, Lind FG. Hyperbaric oxygen therapy for wound complications after surgery in the irradiated head and neck: A review of the literature and a report of 15 consecutive patients. Head Neck. 1997;19:315
  14. Netscher D, Alford EL, Wigoda P, et al: Free composite myo-osseous flap with serratus anterior and rib: Indications in head and neck reconstruction. 20:106, 1998
  15. Schusterman MA, Miller MJ, Reece GP, et al. A single center’s experience with 308 free flaps for repair of head and neck cancer defects. Plast Reconstr Surg. 1994;93:472
  16. Shaha AR, Cordeiro PG, Hidalgo DA, et al. Resection and immediate microvascular reconstruction in the management of osteoradionecrosis of the mandible. Head Neck. 1997;19:406
  17. Urken ML, Buchbinder D, Constantino PD, et al. Oromandibular reconstruction using microvascular composite flaps. Arch Otolaryngol Head Neck. 1998;124:46
  18. Hidalgo DA. Fibula free flap mandibular reconstruction. Clin Plast Surg. 1994;21:25
  19. Rosen IB, Manktelow RT, Zuker RM, et al. Application of microvascular free osteocutaneous flaps in the management of post-radiation recurrent oral cancer. Am J Surg. 1985;150:474
  20. Cheng VST, Wang CC. Osteoradionecrosis of the mandible resulting from external megavoltage radiation therapy. Radiology. 1974;112:685
  21. Jaquiery C, Rohner D, Kunz C, et al. Reconstruction of maxillary and mandibular defects using prefabricated microvascular fibular grafts and osseointegrated dental implants—A prospective study. Clin Oral Implants Res. 2004;15:598

PII: S0278-2391(06)01380-2

doi: 10.1016/j.joms.2005.12.068

Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 3 , Pages 434-438 , March 2007

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