Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 1 , Pages 13-16, January 2007

Hemodynamic Stability in Medically Treated Hypothyroid Patients Undergoing Intravenous Sedation

  • Joseph E. Cillo Jr, DMD

      Affiliations

    • Formerly, Chief Resident, Division of Oral and Maxillofacial Surgery, Parkland Memorial Hospital, The University of Texas Southwestern Medical Center, Dallas, TX; and Currently, Attending Surgeon, Allegheny General Hospital, Pittsburgh, PA.
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Cillo: Allegheny General Hospital, Department of Oral and Maxillofacial Surgery, 320 East North Avenue, Suite 0107, Pittsburgh, PA 15212
    • ,
  • Richard Finn, DDS

      Affiliations

    • Professor, Department of Surgery, Division of Oral and Maxillofacial Surgery and Department of Cell Biology, The University of Texas Southwestern Medical Center, Dallas, TX; and Chief, Oral and Maxillofacial Surgery, Veterans Administration North Texas Health Care System, Dallas, TX.

Purpose

To evaluate the hemodynamic stability of medically treated hypothyroid patients undergoing intravenous sedation for dentoalveolar surgery.

Patients and Methods

A retrospective chart analysis of 20 consecutive white male patients actively being treated for hypothyroidism undergoing intravenous sedation for dentoalveolar surgery. Twenty consecutive normothyroid white male patients undergoing intravenous sedation for dentoalveolar surgery were used as controls. Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP), pulse pressure (PP), peripheral oxygen saturation (SpO2) and pulse were recorded at 5-minute intervals during intravenous sedation.

Results

Statistically significant lower average hemodynamic values were seen in hypothyroid patients compared to normothyroid patients in SBP (P = .05) and PP (P = .003). There were highly significant baseline changes for hypothyroid patients in DBP (P < .001) and MAP (P < .001) and significant baseline changes for normothyroid patients in DBP (P = .03), PP (P = .02) and pulse (P = .03). All changes were maintained within ± 10% of baseline (range, −8.9% to +9.6%).

Conclusions

Intravenous sedation for dentoalveolar surgery in medically treated hypothyroid patients maintains hemodynamic stability.

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PII: S0278-2391(06)01390-5

doi:10.1016/j.joms.2005.12.081

Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 1 , Pages 13-16, January 2007

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