Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 12 , Pages 1761-1766 , December 2006

The Effect of a Single Dose Prednisolone With and Without Diclofenac on Pain, Trismus, and Swelling After Removal of Mandibular Third Molars

  • M. Cemil Buyukkurt, DDS, PhD

      Affiliations

    • Assistant Professor, Department of Oral and Maxillofacial Surgery, Ataturk University, Erzurum, Turkey.
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Buyukkurt: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ataturk University, Erzurum, 25240 Turkey
  • ,
  • Metin Gungormus, DDS, PhD

      Affiliations

    • Associate Professor, Department of Oral and Maxillofacial Surgery, Ataturk University, Erzurum, Turkey.
  • ,
  • Omer Kaya, DDS, PhD

      Affiliations

    • Professor, Department of Oral and Maxillofacial Surgery, Ataturk University, Erzurum, Turkey.

References 

  1. Peterson LJ, Ellis E, Hop JR, et al. In: Contemporary Oral and Maxillofacial Surgery. St Louis: Mosby; 1988;p. 215
  2. Alexander RE, Throndson RR. A review of preoperative corticosteroid use in dentoalveolar surgery. Oral Surg Oral Med Oral Pathol. 2000;90:406
  3. Montgomery MT, Hogg JP, Roberts DL, et al. The use of glucocorticosteroids to lessen the inflammatory sequelae following third molar surgery. J Oral Maxillofac Surg. 1990;48:179
  4. Gersema L, Baker K. Use of corticosteroids in oral surgery. J Oral Maxillofac Surg. 1992;50:270
  5. Milles M, Desjardins PJ. Reduction of postoperative facial swelling by low dose methylprednisolone: An experimental study. J Oral Maxillofac Surg. 1993;51:987
  6. Beirne OR, Hollander B, Francisco S. The effect of methylprednisolone on pain, trismus, and swelling after removal of third molars. Oral Surg Oral Med Oral Pathol. 1986;61:134
  7. Neupert EA, Lee JW, Philput CB, et al. Evaluation of dexamethasone for reduction of postsurgical sequelae of third molar removal. J Oral Maxillofac Surg. 1992;50:1177
  8. Esen E, Tasar F, Akban O. Determination of the antiinflammatory effects of methylprednisolone on the sequelae of third molar surgery. J Oral Maxillofac Surg. 1999;57:1201
  9. Elhag M, Coghlan K, Christmas P. The antiinflammatory effects of dexamethasone and therapeutic ultrasound in oral surgery. Br J Oral Maxillofac Surg. 1985;23:17
  10. Wuolijoki E, Oikarinen VJ, Ylipaavalniemi P, et al. Effective postoperative pain control by preoperative injection of diclofenac. Eur J Clin Pharmacol. 1987;32:249
  11. Hyrkas T, Ylipaavalniemi P, Oikarinen VJ. Preoperative intravenous diclofenac for postoperative pain prevention in outpatients. Br J Oral Maxillofac Surg. 1993;31:351
  12. Westhuijzen AJ, Roelofse JA, Grotepass FW, et al. Randomized double-blind comparison of tiaprofenik acid and diclofenac sodium after third molar surgery. Oral Surg Oral Med Oral Pathol. 1994;78:557
  13. Amin MM, Laskin DM. Prophylactic use of indomethacin for prevention of post surgical complications after removal of impacted third molars. Oral Surg. 1983;55:448
  14. Hyrkas T, Ylipaavalniemi P, Okarinen VJ, et al. Postoperative pain prevention by a single dose formulation of diclofenac producing a steady plasma concentration. J Oral Maxillofac Surg. 1992;50:124
  15. Olstad OA, Skjelbred P. Comparison of the analgesic effect of a corticosteroid and paracetamol in patients with pain after oral surgery. Br J Clin Pharmacol. 1986;22:437
  16. Gersema L, Baker K. Use of corticosteroids in oral surgery. J Oral Maxillofac Surg. 1992;50:270
  17. Holland CS. The influence of methylprednisolone on postoperative swelling following oral surgery. Br J Oral Maxillofac Surg. 1987;25:293
  18. Schultze-Mosgau S, Schmelzeisen R, Schmele H. Use of ibuprofen and methylprednisolone for the prevention of pain and swelling after removal of impacted third molars. J Oral Maxilofac Surg. 1995;53:2
  19. Lin TC, Lui MT, Chang RC. Premedication with diclofenac and prednisolone to prevent postoperative pain and swelling after third molar removal. Zhonghua Yi Xue Za Zhi. 1996;58:40
  20. Hyrkas T, Ylipaavalniemi P, Okarinen VJ, et al. A comparison of diclofenac with and without single-dose intravenous steroid to prevent postoperative pain after third molar removal. J Oral Maxillofac Surg. 1993;51:634
  21. Williamson LW, Lorson EL, Osborn DB. Hypothalamicpituitary-adrenal suppression after short-term dexamethasone therapy for oral surgical procedures. J Oral Surg. 1980;38:20
  22. Swartz SL, Dluhy RG. Corticosteroids: Clinical pharmacology and therapeutic use. Drugs. 1978;16:238
  23. Sisk AL, Bonnington GJ. Evaluation of methylprednisolone and flurbiprofen for inhibition of the postoperative inflammatory response. Oral Surg Oral Med Oral Pathol. 1985;60:137
  24. Beirne OR, Hollander B, Francisco S. The effect of methylprednisolone on pain, trismus, and swelling after removal of third molars. Oral Surg Oral Med Oral Pathol. 1986;61:134

PII: S0278-2391(06)01401-7

doi: 10.1016/j.joms.2005.11.107

Journal of Oral and Maxillofacial Surgery
Volume 64, Issue 12 , Pages 1761-1766 , December 2006