Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 2 , Pages 255-260 , February 2007

Mortality and Causes of Death After Multimodality Treatment for Advanced Oral and Oropharyngeal Cancer

  • Arno Wutzl, MD, DMD

      Affiliations

    • Registrar in Oral and Maxillofacial Surgery, University Hospital Vienna, Vienna, Austria.
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Wutzl: University Hospital for Craniomaxillofacial and Oral Surgery, Medical University Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria
    • ,
  • Oliver Ploder, MD, DMD, PhD

      Affiliations

    • Professor and Department Head, Department of Oral and Maxillofacial Surgery, Hospital Feldkirch, Feldkirch, Austria.
    • ,
  • Christian Kermer, MD, DMD

      Affiliations

    • Assistant Professor, University Hospital for Craniomaxillofacial and Oral Surgery, Medical University Vienna, Vienna, Austria.
    • ,
  • Werner Millesi, MD, DMD, PhD

      Affiliations

    • Professor and Department Head, Department of Oral and Maxillofacial Surgery, Hospital Lainz, Vienna, Austria.
    • ,
  • Rolf Ewers, MD, DMD, PhD

      Affiliations

    • Professor and Department Head, University Hospital for Craniomaxillofacial and Oral Surgery, Medical University Vienna, Vienna, Austria.
    • ,
  • Clemens Klug, MD, DMD, PhD

      Affiliations

    • Assistant Professor, University Hospital for Craniomaxillofacial and Oral Surgery, Medical University Vienna, Vienna, Austria.

References 

  1. Mohr C, Bohndorf W, Carstens J, et al. Preoperative radiochemotherapy and radical surgery in comparison with radical surgery alone: A prospective, multicentric, randomized DOSAK study of advanced squamous cell carcinoma of the oral cavity and the oropharynx (a 3-year follow-up). Int J Oral Maxillofac Surg. 1994;23:140
  2. Kirita T, Ohgi K, Shimooka H, et al. Preoperative concurrent chemoradiotherapy plus radical surgery for advanced squamous cell carcinoma of the oral cavity: An analysis of long-term results. Oral Oncol. 1999;35:597
  3. De Vries N, van der Waal I, Snow GB. Multiple primary tumours in oral cancer. Int J Oral Maxillofac Surg. 1986;15:85
  4. Jones AS, Morar P, Phillips DE, et al. Second primary tumors in patients with head and neck squamous cell carcinoma. Cancer. 1995;75:1343
  5. Reid BC, Alberg AJ, Klassen AC, et al. Comorbidity and survival of elderly head and neck carcinoma patients. Cancer. 2001;92:2109
  6. Day GL, Blot WJ. Second primary tumors in patients with oral cancer. Cancer. 1992;70:14
  7. Leon X, Quer M, Diez S, et al. Second neoplasm in patients with head and neck cancer. Head Neck. 1999;21:204
  8. Woolgar JA, Rogers S, West CR, et al. Survival and patterns of recurrence in 200 oral cancer patients treated by radical surgery and neck dissection. Oral Oncol. 1999;35:257
  9. Dobrowsky W, Dobrowsky E, Strassl H, et al. Combined modality treatment of advanced cancers of the oral cavity and oropharynx. Int J Radiat Oncol Biol Phys. 1991;20:239
  10. Leitner C, Rogers SN, Lowe D, et al. Death certification in patients whose primary treatment for oral and oropharyngeal carcinoma was operation: 1992-1997. Br J Oral Maxillofac Surg. 2002;39:204
  11. Eckardt A, Rades D, Rudat V, et al. Prospective phase II study of neoadjuvant radiochemotherapy in advanced operable carcinoma of the mouth cavity: 3-year outcome. Mund Kiefer Gesichtschir. 2002;6:117
  12. Licitra L, Grandi C, Guzzo M, et al. Primary chemotherapy in resectable oral cavity squamous cell cancer: A randomized controlled trial. J Clin Oncol. 2003;15:327
  13. Hermann RM, Krech R, Hartlapp J, et al. The value of qualitative regression grading as a prognostic factor for survival after preoperative radiochemotherapy in patients with advanced head and neck cancer. Strahlenther Onkol. 2001;177:277
  14. Wax MK, Myers LL, Gabalski EC, et al. Positron emission tomography in the evaluation of synchronous lung lesions in patients with untreated head and neck cancer. Arch Otolaryngol Head Neck Surg. 2002;128:703
  15. Diederich S, Wormanns D, Heindel W. Lung cancer screening with low-dose CT. Eur J Radiol. 2003;45:2

 The ethical committee of the Medical University of Vienna approved this study.This study was supported by the “Jubiläumsfonds der Österreichischen Nationalbank,” project no. 10701 (coordinated by Dr Clemens Klug). The ethical committee of the Medical University of Vienna approved this study.

PII: S0278-2391(06)01760-5

doi: 10.1016/j.joms.2006.09.007

Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 2 , Pages 255-260 , February 2007

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