Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 7 , Pages 1292-1296 , July 2007

Head and Neck Keloid: Treatment by Core Excision and Delayed Intralesional Injection of Steroid

  • Peter Donkor, BDS, MDSc, MSc, FRACDS, FWACS, FGCS

      Affiliations

    • Consultant, Maxillofacial Surgery Unit, Department of Surgery, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
    • Corresponding Author InformationAddress correspondence and reprint requests to Prof Peter Donkor: Maxillofacial Unit, Department of Surgery, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Komfo Anokye Teaching Hospital, 1 Bantama High Street, Kumasi, Ghana, West Africa

References 

  1. Alhady SM, Sivanantharajah K. Keloids in various races (A review of 175 cases). Plast Reconstr Surg. 1969;44:564
  2. Ramakrishnan KM, Thomas KP, Sundararajan CR. Study of 1,000 patients with keloids in South India. Plast Reconstr Surg. 1974;53:276
  3. Datubo-Brown DD. Keloids: A review of the literature. Br J Plast Surg. 1990;43:70
  4. Crockett DJ. Regional keloid susceptibility. Br J Plast Surg. 1964;17:245
  5. Nessen F, Spauven P, Schalkwyk J, et al. On the nature of hypertrophic scars and keloids: A review. Plast Reconstr Surg. 1999;104:1440
  6. Abergel RP, Pizzurro D, Meeker CA, et al. Biochemical composition of the connective tissue in keloids and analysis of collagen metabolism in keloid fibroblast cultures. J Invest Dermatol. 1985;84:384
  7. Kazeem AA. The immunological aspects of keloid tumor formation. J Surg Oncol. 1988;38:16
  8. Ala-Kokko L, Rintala A, Savolainen ER. Collagen gene expression in keloids: Analysis of collagen metabolism and type I, III, IV, and V procollagen mRNAs in keloid tissue and keloid fibroblast cultures. J Invest Dermatol. 1987;89:238
  9. Ehrlich HP, Desmouliere A, Diegelmann RF, et al. Morphological and immunochemical differences between keloid and hypertrophic scar. Am J Pathol. 1994;145:105
  10. Kikuchi K, Kadono T, Takehara K. Effects of various growth factors and histamine on cultured keloid fibroblasts. Clin Lab Invest. 1995;190:4
  11. Greenhalgh DG. The role of apoptosis in wound healing. Int J Biochem Cell Biol. 1998;30:1019
  12. Meenakshi J, Jayaraman V, Ramakrishnan KM, et al. Keloids and hypertrophic scars: A review. Indian J Plast Surg. 2005;38:175
  13. Kiil J. Keloids treated with topical injections of triamcinolone acetonide (kenalog) (Immediate and long-term results). Scand J Plast Reconstr Surg. 1977;11:169
  14. Shons AR, Press BH. The treatment of earlobe keloids by surgical excision and postoperative triamcinolone injection. Ann Plast Surg. 1983;10:480
  15. Golladay ES. Treatment of keloids by single intraoperative perilesional injection of repository steroid. South Med J. 1988;81:736
  16. Berman B, Bieley N. Adjunct therapies to surgical management of keloids. Dermatol Surg. 1996;22:126
  17. Lee Y, Minn K-W, Baek R-M. A new surgical treatment of keloid: Keloid core excision. Ann Plast Surg. 2001;46:135
  18. Muti E, Ponzio E. Cryotherapy in the treatment of keloids. Ann Plast Surg. 1983;11:227
  19. Sherman R, Rosenfeld H. Experience with the Nd:YAG laser in the treatment of keloid scars. Ann Plast Surg. 1988;21:231
  20. Van den Brenk HAS, Minty CCJ. Radiation in the management of hypertrophic scars and keloids. Br J Surg. 1959;47:595
  21. Edsmyr F, Larsson LG, Onyango J, et al. Radiation therapy in the treatment of keloids in East Africa. Acta Radiol Ther Phys Biol. 1974;13:102
  22. Sallstrom KO, Larson O, Heden P, et al. Treatment of keloids with surgical excision and postoperative x-ray radiation. Scand J Plast Reconstr Surg Hand Surg. 1989;23:211
  23. Sawadow Y, Soni K. Hydration and occlusive therapy for hypertrophic scars and keloids. Brit J Plast Surg. 1992;45:599
  24. Carr-Collins J. Pressure techniques for the prevention of hypertrophic scar. Clin Plast Surg. 1992;19:733
  25. Cheng JC, Evans JH, Leung KS, et al. Pressure therapy in the treatment of post-burn hypertrophic scar–A critical look into its usefulness and fallacies by pressure monitoring. Burns Incl Therm Inj. 1984;10:154
  26. Gold MH. A controlled clinical trial of topical silicone gel sheeting in the treatment of hypertrophic scars and keloids. J Am Acad Dermatol. 1994;30:506
  27. Fulton J. Silicone gel sheeting for the prevention and management of evolving hypertrophic and keloid scars. Dermatol Surg. 1995;21:945
  28. Berman B, Flores F. Comparison of a silicone gel-filled cushion and silicon gel sheeting for the treatment of hypertrophic or keloid scars. Dermatol Surg. 1999;25:484
  29. Shamberger R, Tabbot T, Tripton H, et al. The effect of ultrasonic and thermal treatment on wounds. Plast Reconstr Surg. 1981;68:860
  30. Granstein RD, Rook A, Flotte TJ, et al. A controlled trial of intralesional recombinant interferon-gamma in the treatment of keloidal scarring (Clinical and histologic findings). Arch Dermatol. 1990;126:1295

PII: S0278-2391(06)01946-X

doi: 10.1016/j.joms.2006.10.049

Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 7 , Pages 1292-1296 , July 2007

Article Tools

* Image Usage & Resolution