Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 6 , Pages 1149-1154 , June 2007

Oral Surgery in Patients on Anticoagulant Treatment Without Therapy Interruption

  • Giovanni B. Ferrieri, MD, DMD

      Affiliations

    • Clinical Professor, Departments of Medicine, Surgery, and Dentistry, Università degli Studi di Milano, Milano, Italy.
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Ferrieri: Università degli Studi di Milano, Via Beldiletto 1/3, 20142 Milano, Italy
    • ,
  • Stefano Castiglioni, DDS

      Affiliations

    • PhD Student, Departments of Medicine, Surgery, and Dentistry, Università degli Studi di Milano, Milano, Italy.
    • ,
  • Daniela Carmagnola, DDS, PhD

      Affiliations

    • Research Associate, Departments of Medicine, Surgery, and Dentistry, Università degli Studi di Milano, Milano, Italy.
    • ,
  • Marco Cargnel, DDS

      Affiliations

    • Clinical Professor, Departments of Medicine, Surgery, and Dentistry, Università degli Studi di Milano, Milano, Italy.
    • ,
  • Laura Strohmenger, MD, DMD

      Affiliations

    • Professor and Chairman, Departments of Medicine, Surgery, and Dentistry, Università degli Studi di Milano, Milano, Italy.
    • ,
  • Silvio Abati, MD, DMD

      Affiliations

    • Associate Professor, Departments of Medicine, Surgery, and Dentistry, Università degli Studi di Milano, Milano, Italy.

References 

  1. Scully C, Wolff A. Oral surgery in patients on anticoagulant therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;94:57
  2. Little JW, Falace DA, Miller CS, et al. Dental Management of the Medically Compromised Patient. Ed 6.. St Louis, MO: Mosby; 2002;
  3. Dunn AS, Turpie AG. Perioperative management of patients receiving oral anticoagulants: A systematic review. Arch Intern Med. 2003;163:901
  4. Wahl MJ. Dental surgery in anticoagulated patients. Arch Intern Med. 1998;158:1610
  5. Devani P, Lavery KM, Howell CJ. Dental extractions in patients on warfarin: Is alteration of anticoagulant regime necessary?. Br J Oral Maxillofac Surg. 1998;36:107
  6. Giglio J. Complications of dentoalveolar surgery. In:  Kwon P,  Laskin D editor. Clinician’s Manual of Oral and Maxillo-Facial Surgery. Ed 3.. Chicago, IL: Quintessence; 1997;p. 271–272
  7. Blinder D, Manor Y, Martinowitz U, et al. Dental extractions in patients maintained on oral anticoagulant therapy: Comparison of INR value with occurrence of postoperative bleeding. Int J Oral Maxillofac Surg. 2001;30:518
  8. Beirne OR. Evidence to continue oral anticoagulant therapy for ambulatory oral surgery. J Oral Maxillofac Surg. 2005;63:540
  9. Todd DW. Evidence to support an individualized approach to modification of oral anticoagulant therapy for ambulatory oral surgery. J Oral Maxillofac Surg. 2005;63:536
  10. Carter G, Goss A. Tranexamic acid mouthwash--a prospective randomized study of a 2-day regimen vs 5-day regimen to prevent postoperative bleeding in anticoagulated patients requiring dental extractions. Int J Oral Maxillofac Surg. 2003;32:504
  11. Carter G, Goss A, Lloyd J, et al. Tranexamic acid mouthwash versus autologous fibrin glue in patients taking warfarin undergoing dental extractions: A randomized prospective clinical study. J Oral Maxillofac Surg. 2003;61:1432
  12. Dajani AS, Taubert KA, Wilson W, et al. Prevention of bacterial endocarditis: Recommendations by the American Heart Association. Clin Infect Dis. 1997;25:1448
  13. Perusse R, Goulet JP, Turcotte JY. Contraindications to vasoconstrictors in dentistry: Part II (Hyperthyroidism, diabetes, sulfite sensitivity, cortico-dependent asthma, and pheochromocytoma). Oral Surg Oral Med Oral Pathol. 1992;74:687
  14. Evans IL, Sayers MS, Gibbons AJ, et al. Can warfarin be continued during dental extraction? (Results of a randomized controlled trial). Br J Oral Maxillofac Surg. 2002;40:248

PII: S0278-2391(06)02104-5

doi: 10.1016/j.joms.2006.11.015

Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 6 , Pages 1149-1154 , June 2007

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