Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 10 , Pages 1951-1957 , October 2007

Autologous Injectable Tissue-Engineered Cartilage by Using Platelet-Rich Plasma: Experimental Study in a Rabbit Model

  • Wei Wu, DDS, PhD

      Affiliations

    • Resident, Department of Oral and Maxillofacial Surgery, School of Stomatology, Fourth Military Medical University, Xi’an, P.R. China.
  • ,
  • Fulin Chen, PhD

      Affiliations

    • Professor, Rege Laboratory of Tissue Engineering, Faculty of Life Science, Northwest University, Xi’an, P.R. China.
  • ,
  • Yanpu Liu, DDS, PhD

      Affiliations

    • Professor and Director, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi’an, P.R. China.
  • ,
  • Qin Ma, DDS, PhD

      Affiliations

    • Associate Professor, Department of Oral and Maxillofacial Surgery, School of Stomatology, Fourth Military Medical University, Xi’an, P.R. China.
  • ,
  • Tianqiu Mao, DDS

      Affiliations

    • Professor, Department of Oral and Maxillofacial Surgery, School of Stomatology, Fourth Military Medical University, Xi’an, P.R. China.
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Mao: College of Stomatology, Fourth Military Medical University, Department of Oral and Maxillofacial Surgery, Chang Le Xi Road 146#, Xi’an, P.R. China

References 

  1. Sittinger M, Hutmacher DW, Risbud MV. Current strategies for cell delivery in cartilage and bone regeneration. Curr Opin Biotechnol. 2004;15:411
  2. Haddo O, Mahroof S, Higgs D, et al. The use of chondrogide membrane in autologous chondrocyte implantation. Knee. 2004;11:51
  3. Marcacci M, Berruto M, Brocchetta D, et al. Articular cartilage engineering with Hyalograft C: 3-year clinical results. Clin Orthop Relat Res. 2005;435:96
  4. Atala A, Cima LG, Kim W, et al. Injectable alginate seeded with chondrocytes as a potential treatment for vesicoureteral reflux. J Urol. 1993;150:745
  5. Liu Y, Chen F, Liu W, et al. Repairing large porcine full-thickness defects of articular cartilage using autologous chondrocyte-engineered cartilage. Tissue Eng. 2002;8:709
  6. Aminuddin BS, Cao Y, Weng Y, et al. Engineering autologous cartilage in the shape of a helix using an injectable hydrogel scaffold. Laryngoscope. 2000;110:1694
  7. Temenoff JS, Mikos AG. Injectable biodegradable materials for orthopedic tissue engineering. Biomaterials. 2000;21:2405
  8. Kulseng B, Skjak-Braek G, Ryan L, et al. Transplantation of alginate microcapsules. Transplantation. 1999;67:978
  9. Chan-Park MB, Zhu AP, Shen JY, et al. Novel photopolymerizable biodegradable triblock polymers for tissue engineering scaffolds: Synthesis and characterization. Macromol Biosci. 2004;14:665
  10. Cho JH, Kim SH, Park KD, et al. Chondrogenic differentiation of human mesenchymal stem cells using a thermosensitive poly (N-isopropylacrylamide) and water-soluble chitosan copolymer. Biomaterials. 2004;25:5743
  11. Intini G, Andreana S, Margarone JE, et al. Engineering a bioactive matrix by modifications of calcium sulfate. Tissue Eng. 2002;8:997
  12. Yamada Y, Ueda M, Naiki T, et al. Autogenous injectable bone for regeneration with mesenchymal stem cells and platelet-rich plasma: Tissue-engineered bone regeneration. Tissue Eng. 2004;10:955
  13. Bjornsson S. Simultaneous preparation and quantitation of proteoglycans by precipitation with Alcian blue. Anal Biochem. 1993;210:282
  14. Stock UA, Vacanti JP. Tissue engineering: Current state and prospects. Annu Rev Med. 2001;52:443
  15. Kose GT, Korkusuz F, Ozkul A, et al. Tissue engineered cartilage on collagen and PHBV matrices. Biomaterials. 2005;26:5187
  16. Abukawa H, Shin M, Williams WB, et al. Reconstruction of mandibular defects with autologous tissue-engineered bone. J Oral Maxillofac Surg. 2004;62:601
  17. Kaufman MR, Tobias GW. Engineering cartilage growth and development. Clin Plast Surg. 2003;30:539
  18. Fussenegger M, Meinhart J, Hobling W, et al. Stabilized autologous fibrin-chondrocyte constructs for cartilage repair in vivo. Ann Plast Surg. 2003;51:493
  19. Paige KT, Cima LG, Yaremchuk MJ, et al. Injectable cartilage. Plast Reconstr Surg. 1995;96:1390
  20. Ibusuki S, Fujii Y, Iwamoto Y, et al. Tissue-engineered cartilage using an injectable and in situ gelable thermoresponsive gelatin: Fabrication and in vitro performance. Tissue Eng. 2003;9:371
  21. Kanno T, Takahashi T, Tsujisawa T, et al. Platelet-rich plasma enhances human osteoblast-like cell proliferation and differentiation. J Oral Maxillofac Surg. 2005;63:362
  22. Darling EM, Athanasiou KA. Rapid phenotypic changes in passaged articular chondrocyte subpopulations. J Orthop Res. 2005;23:425
  23. Shieh SJ, Terada S, Vacanti JP. Tissue engineering auricular reconstruction: in vitro and in vivo studies. Biomaterials. 2004;25:1545
  24. Galois L, Hutasse S, Cortial D, et al. Bovine chondrocyte behaviour in three-dimensional type I collagen gel in terms of gel contraction, proliferation and gene expression. Biomaterials. 2006;27:79
  25. Silverman RP, Passaretti D, Huang W, et al. Injectable tissue-engineered cartilage using a fibrin glue polymer. Plast Reconstr Surg. 1999;103:1809

 This work was funded by the National Natural Science Foundation (P.R. China), grant nos. 30270373 and 30370374.

PII: S0278-2391(06)02107-0

doi: 10.1016/j.joms.2006.11.044

Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 10 , Pages 1951-1957 , October 2007