Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 9 , Pages 1725-1733 , September 2007

Characterization of 3 Oral Squamous Cell Carcinoma Cell Lines With Different Invasion and/or Metastatic Potentials

This article was presented at the AAOMS 88th Annual Meeting October 4, 2006, where it was the recipient of the Straumann Award.

  • N. Fazil Erdem, DDS, MS

      Affiliations

    • Intern, Department of Oral and Maxillofacial Surgery, PhD Candidate in Comparative and Experimental Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN.
    • ,
  • Eric R. Carlson, DMD, MD

      Affiliations

    • Professor and Chairman, Department of Oral and Maxillofacial Surgery, University of Tennessee Graduate School of Medicine, Knoxville, TN.
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Carlson: Department of Oral and Maxillofacial Surgery, University of Tennessee Graduate School of Medicine, 1930 Alcoa Highway, Suite 335, Knoxville, TN 37920
    • ,
  • David A. Gerard, PhD

      Affiliations

    • Associate Professor, Department of Oral and Maxillofacial Surgery, University of Tennessee Graduate School of Medicine, Knoxville, TN.
    • ,
  • Albert T. Ichiki, PhD

      Affiliations

    • Professor and Chairman, Department of Medical Genetics, University of Tennessee Graduate School of Medicine, Knoxville, TN.
    • Dr Albert T. Ichiki died in 2007.

References 

  1. Neville BW, Damm DD, Allen CM, et al. Oral and Maxillofacial Pathology. In: (ed 1). Philadelphia, PA: WB Saunders; 1996;p. 295
  2. Hiraga T, Tanaka S, Ikegame M, et al. Morphology of bone metastasis. Eur J Cancer. 1998;34:230
  3. Roodman D. Biology of osteoclast activation in cancer. J Clin Oncol. 2001;19:3562
  4. Semba I, Matsuuchi H, Miura Y. Histomorphometric analysis of osteoclastic resorption in bone directly invaded by gingival squamous cell carcinoma. J Oral Pathol Med. 1996;25:429
  5. Nakai M, Mundy GR, Williams PJ, et al. A synthetic antagonist to laminine inhibits the formation of osteolytic metastases by human melanoma cells in nude mice. Cancer Res. 1992;52:5395
  6. Kawamata H, Nakashiro K, Uchida D, et al. Possible contribution of active MMP-2 to lymph-node metastasis and secreted cathepsin L to bone invasion of newly established human oral-squamous-cancer cell lines. Int J Cancer. 1997;70:120
  7. Kusukawa J, Harada H, Shima I, et al. The significance of epidermal growth factor receptor and matrix metalloproteinase-3 in squamous cell carcinoma of the oral cavity. Eur J Cancer B Oral Oncol. 1996;32B:217
  8. Uchida D, Kawamata H, Nakashiro K, et al. Low-dose retinoic acid enhances in vitro invasiveness of human oral squamous-cell carcinoma cell lines. Br J Cancer. 2001;85:122
  9. Hida K, Shindoh M, Yoshida K, et al. Expression of E1AF, an ets-family transcription factor, is correlated with the invasive phenotype of oral squamous cell carcinoma. Oral Oncol. 1997;33:426
  10. Bordador LC, Li X, Toole B, et al. Expression of EMMPRIN by oral squamous cell carcinoma. Int J Cancer. 2000;85:347
  11. Kawasaki G, Kato Y, Mizuno A. Cathepsin expression in oral squamous cell carcinoma: Relationship with clinicopathologic factors. Oral Surg Oral Med Oral Pathol. 2002;93:446
  12. Hong SD, Hong SP, Lee J, et al. Expression of matrix metalloproteinase-2 and -9 in oral squamous cell carcinomas with regard to the metastatic potential. Oral Oncol. 2000;36:207
  13. Koyama S. Enhanced cell surface expression of matrix metalloproteinases and their inhibitors, and tumor-induced host response in progression of human gastric carcinoma. Dig Dis Sci. 2004;49:1621
  14. Vicente JC, Fresno MF, Villalain L, et al. Expression and clinical significance of matrix metalloproteinases-2 and metalloproteinases-9 in oral squamous cell carcinoma. Oral Oncol. 2005;42:283
  15. Tsai CH, Hsieh YS, Yang SF, et al. Matrix metalloproteinase-2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: Preliminary observations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95:710
  16. Parks WC, Mecham RP. Matrix Metalloproteinases. (ed 1). San Diego, CA: Academic Press; 1998;
  17. Ziober BL, Turner MA, Palefsky JM, et al. Type I collagen degradation by invasive oral squamous cell carcinoma. Oral Oncol. 2000;36:365
  18. Turk V. Proteases: New Perspectives. In: (ed 1). Basel, Switzerland: Birkhäuser Verlag; 1999;pp 113, 212
  19. Kusukawa J, Sasaguri Y, Shima I, et al. Production of matrix metalloproteinase 2 (gelatinase/type IV collagenase) and 3 (stromelysin) by cultured oral squamous cell carcinoma. J Oral Pathol Med. 1992;21:221
  20. Shima I, Sasaguri Y, Kusukawa J. Production of matrix metalloproteinase 9 (92-kDa gelatinase) by human esophageal squamous cell carcinoma in response to epidermal growth factor. Br J Cancer. 1993;67:721
  21. Vigneswaran N, Wu J, Zacharias W. Upregulation of cystatin M during the progression of oropharyngeal squamous cell carcinoma from primary tumor to metastasis. Oral Oncol. 2003;39:559
  22. Shima I, Sasaguri Y, Kusukawa J, et al. Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. Cancer. 1992;70:2747
  23. Kusukawa J, Sasaguri Y, Shima I, et al. Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. Am J Clin Pathol. 1993;99:18
  24. Kato K, Hara A, Kuno T, et al. Matrix metalloproteinases 2 and 9 in oral squamous cell carcinomas: Manifestation and localization of their activity. J Cancer Res Clin Oncol. 2005;131:340
  25. Miyajima Y, Nakano R, Morimatsu M. Analysis of expression of matrix metalloproteinase-2 and -9 in hypopharyngeal squamous cell carcinoma by in situ hybridization. Ann Otol Rhinol Laryngol. 1995;91:207
  26. Charous SJ, Stricklin GP, Nanney LB, et al. Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase in head and neck squamous cell carcinoma. Ann Otol Rhinol Laryngol. 1997;106:271
  27. Guntinas-Lichius O, Wittekindt C. The role of growth factors for disease and therapy in diseases of head and neck. DNA Cell Biol. 2003;22:593
  28. Scully C, Field JK, Tanzawa H. Genetic aberration in oral or head and neck squamous cell carcinoma 2: Chromosomal aberrations. Oral Oncol. 2000;36:311
  29. Turk B, Turk D, Turk V. Lysosomal cysteine proteases: More than scavengers. Biochim Biophys Acta. 2000;1477:98

PII: S0278-2391(06)02208-7

doi: 10.1016/j.joms.2006.11.034

Journal of Oral and Maxillofacial Surgery
Volume 65, Issue 9 , Pages 1725-1733 , September 2007

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