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Volume 66, Issue 1, Pages 16-20 (January 2008)


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Effect of Chemotherapy on Primary Mucosa-Associated Lymphoid Tissue Lymphoma of the Orbit

Ioannis Dimitrakopoulos, MD, DDSCorresponding Author Informationemail address, Grigorios Venetis, MD, DDS, Vasiliki Kaloutsi, MD, Damianos Sotiropoulos, MD§, Constantinos Papadimitriou, MD

Purpose

To present a treatment plan for localized mucosa-associated lymphoid tissue lymphoma of the orbit in order to preserve vital structures and function from the side effects of radiotherapy.

Materials and Methods

Study of 2 clinical cases by means of clinical and radiologic examination, with 2 and 3 years follow-up, respectively.

Results

Immediate remission of the disease after 6 cycles of chemotherapy, with no signs of recurrence after 2 and 3 years. Clinical examination of the oculomotor mechanism and visual activity gave excellent results.

Conclusion

Although radiotherapy is preferable for localized lymphoproliferative lesions, chemotherapy should also be considered as an effective treatment that preserves the integrity and function of the ocular adnexa.

 Associate Professor, University Clinic of Oral and Maxillofacial Surgery, “G. Papanikolaou” General Hospital, Thessaloniki, Greece.

 Lecturer, University Clinic of Oral and Maxillofacial Surgery, “G. Papanikolaou” General Hospital, Thessaloniki, Greece.

 Associate Professor, Department of Pathology, School of Medicine, Aristotle University, Thessaloniki, Greece.

§ Pathologist, Department of Hematology and Bone Marrow Transplantation Unit, “G. Papanikolaou” General Hospital, Thessaloniki, Greece.

 Professor and Head, Department of Pathology, School of Medicine, Aristotle University, Thessaloniki, Greece.

Corresponding Author InformationAddress correspondence and reprint requests to Dr Dimitrakopoulos: P Mela 28, 546 22, Thessaloniki, Greece

PII: S0278-2391(07)00485-5

doi:10.1016/j.joms.2007.04.018


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