Journal of Oral and Maxillofacial Surgery
Volume 66, Issue 3 , Pages 441-445 , March 2008

Effectiveness of Chlorhexidine Gel Versus Chlorhexidine Rinse in Reducing Alveolar Osteitis in Mandibular Third Molar Surgery

  • Pilar Hita-Iglesias, DDS, PhD

      Affiliations

    • Assistant Professor and Master in Oral Surgery; and Clinical Lecturer, Department of Oral and Maxillofacial Surgery, University of Michigan, Ann Arbor, MI.
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Hita-Iglesias: University of Michigan, Oral and Maxillofacial Surgery, 1500 Medical Center Dr, Ann Arbor, MI 48109-0018
    • ,
  • Daniel Torres-Lagares, DDS, PhD

      Affiliations

    • Assistant Professor, Master in Oral Surgery, Department of Dentistry, University of Seville, Seville, Spain.
    • ,
  • Rafael Flores-Ruiz, DDS

      Affiliations

    • Assistant Professor, Master in Oral Surgery, Department of Dentistry, University of Seville, Seville, Spain.
    • ,
  • Natale Magallanes-Abad, DDS

      Affiliations

    • Assistant Professor, Master in Oral Surgery, Department of Dentistry, University of Seville, Seville, Spain.
    • ,
  • Marta Basallote-Gonzalez, DDS

      Affiliations

    • Research Assistant, Master in Oral Surgery, Department of Dentistry, University of Seville, Seville, Spain.
    • ,
  • Jose-Luis Gutierrez-Perez, MD, DDS

      Affiliations

    • Professor and Chairman, Department of Dentistry, University of Seville, Seville, Spain.

References 

  1. Crawford JY. Dry socket. Dent Cosmos. 1896;38:929
  2. Swanson AE. Prevention of dry socket: An overview. Oral Surg Oral Med Oral Pathol. 1990;70:131
  3. Swanson AE. A double-blind study on effectiveness of tetracycline in reducing the incidence of fibrinolytic alveolitis. J Oral Maxillofac Surg. 1989;47:165
  4. Moore JW, Brekke JH. Foreign body giant cell reaction related to placement of tetracycline-treated polylactic acid: Report of 18 cases. J Oral Maxillofac Surg. 1990;48:808
  5. Trieger N, Schlagel GD. Preventing dry socket (A simple procedure that works). J Am Dent Assoc. 1991;2:67
  6. Blum IR. Contemporary views on dry socket (alveolar osteitis): A clinical appraisal of standardization, aetiopathogenesis and management: A critical review. Int J Oral Maxillofac Surg. 2002;31:309
  7. García Murcia MJ, Peñarrocha Diago M. Alveolitis seca: Revisión de la literatura y metaanálisis. Rev Actual Odontoestomatol Esp. 1994;44:25
  8. Barclay JK. Metronidazole and dry socket: Prophylactic use in mandibular third molar removal complicated by non-acute pericoronitis. N Z Dent J. 1987;83:71
  9. Fridrich KL, Olson RA. Alveolar osteitis following surgical removal of mandibular third molars. Anesth Prog. 1990;37:32
  10. Rozanis J, Schofield ID, Warren BA. Is dry socket preventable?. Dent J. 1977;43:233
  11. Schow SR. Evaluation of postoperative localized osteitis in mandibular third molar surgery. Oral Surg Oral Med Oral Pathol. 1974;38:352
  12. Ariza E, González J, Boneu F, et al. Incidencia de la alveolitis seca, tras la exodoncia quirúrgica de terceros molares mandibulares en nuestra Unidad de Cirugía Oral. Rev Esp Cir Oral Maxilofac. 1999;21:214
  13. Rood JP, Murgatroyd J. Metronidazole in the prevention of “dry socket”. Br J Oral Surg. 1979;17:62
  14. Jaafar N, Nor GM. The prevalence of post-extraction complications in an outpatient dental clinic in Kuala Lumpur, Malaysia: A retrospective survey. Singapore Dent J. 2000;23:24
  15. Larsen PE. The effect of a chlorhexidine rinse on the incidence of alveolar osteitis following the surgical removal of impacted mandibular third molar. J Oral Maxillofac Surg. 1991;49:932
  16. Ragno JR, Szkutnik AJ. Evaluation of 0.12% chlorhexidine rinse on the prevention of alveolar osteitits. Oral Surg Oral Med Oral Pathol. 1991;72:524
  17. Berwick JE, Lessin ME. Effects of a chlorhexidine gluconate oral rinse on the incidence of alveolar osteitis in mandibular third molar surgery. J Oral Maxillofac Surg. 1990;48:444
  18. Larsen PE. Alveolar osteitis after surgical removal of impacted mandibular third molars (Identification of the patient at risk). Oral Surg Oral Med Oral Pathol. 1992;73:393
  19. Ritzau M, Hillerup S, Branebjerg PE, et al. Does metronidazole prevent alveolitis sicca dolorosa? (A double-blind, placebo-controlled clinical study). J Oral Maxillofac Surg. 1992;21:299
  20. Bloomer CR. Alveolar osteitis prevention by immediate placement of medicated packing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;90:282
  21. Caso A, Hung LK, Beirne OR. Prevention of alveolar osteitis with clorhexidine: A meta-analytic review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:155
  22. Koerner KR. The removal of impacted third molars (Principles and procedures). Dent Clin North Am. 1994;38:255
  23. Sweet JB, Butler DP. Increased incidence of postoperative localized osteitis in mandibular third molar surgery associated with patients using oral contraceptives. Am J Obstet Gynecol. 1977;127:518
  24. Sweet JB, Butler DP. Predisposing and operative factors: Effect on the incidence of localized osteitis in mandibular third-molar surgery. Oral Surg Oral Med Oral Pathol. 1978;46:206
  25. Fotos PG, Koorbusch GF, Sarasin DS, et al. Evaluation of intra-alveolar chlorhexidine dressings after removal of impacted mandibular third molars. Oral Surg Oral Med Oral Pathol. 1992;73:383
  26. Tjernberg A. Influence of oral hygiene measures on the development of alveolitis sicca dolorosa after surgical removal of mandibular third molar. Int J Oral Surg. 1979;8:430
  27. Delilbasi C, Saracoglu U, Keskin A. Effects of 0.2% chlorhexidine gluconate and amoxicillin plus clavulanic acid on the prevention of alveolar osteitis following mandibular third molar extractions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;94:301
  28. Larsen PE. Use of chlorhexidine to prevent alveolar osteitis. J Oral Maxillofac Surg. 1990;48:1244
  29. Torres D, Gutiérrez JL, Infante P, et al. Randomized, double-blind study on effectiveness of intra-alveolar clorhexidine gel in reducing the incidence of alveolar osteitis in mandibular third molar surgery. Int J Oral Maxillofac Surg. 2006;35:348
  30. Hermesch CB, Hilton TJ, Biesbrock AR, et al. Perioperative use of 0.12% chlorhexidine gluconate for the prevention of alveolar osteitis (Efficacy and risk factor analysis). Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;85:381
  31. Bonine FL. Effect of chlorhexidine rinse on the incidence of dry socket in impacted mandibular third molar extraction sites. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995;79:154

PII: S0278-2391(07)01481-4

doi: 10.1016/j.joms.2007.06.641

Journal of Oral and Maxillofacial Surgery
Volume 66, Issue 3 , Pages 441-445 , March 2008

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