Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 2 , Pages 251-256 , February 2009

Sclerotherapy of Microcystic Lymphatic Malformations in Oral and Facial Regions

  • Yi Bai, DDS MSc

      Affiliations

    • Oral Surgeon, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, People's Republic of China
    • ,
  • Jun Jia, DDS, PhD

      Affiliations

    • Associate Clinical Professor, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, People's Republic of China
    • ,
  • Xing-Xing Huang, DDS, MSc

      Affiliations

    • Lecturer, Key Laboratory for Oral Biomedical Engineering of Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, People's Republic of China
    • ,
  • Mohd Jamal Alsharif, DDS, MSc

      Affiliations

    • Resident in Chief, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, People's Republic of China
    • ,
  • Ji-Hong Zhao, DDS, MSc

      Affiliations

    • Clinical Professor, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, People's Republic of China
    • ,
  • Yi-Fang Zhao, DDS, MSc

      Affiliations

    • Professor, Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, People's Republic of China
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Zhao: Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, 237 LuoYu Road, Wuhan, People's Republic of China 430079

References 

  1. Tanigawa N, Shimomatsuya T, Takahashj K, et al. Treatment of cystic hygroma and lymphangioma with the use of bleomycin fat emulsion. Cancer. 1987;60:741
  2. Mathur NN, Rana I, Bothra R, et al. Bleomycin sclerotherapy in congenital lymphatic and vascular malformations of head and neck. Int J Pediatr Otorhinolaryngol. 2005;69:75
  3. Ogita S, Tsuto T, Tokiwa K, et al. Intracystic injection of OK-432: A new sclerosing therapy for cystic hygroma in children. Br J Surg. 1987;74:690
  4. Sanlialp I, Karnak I, Tanyel FC, et al. Sclerotherapy for lymphangioma in children. Int J Pediatr Otorhinolaryngol. 2003;67:795
  5. Qin ZP, Xin ZF, Ren L, et al. Long term results of intratumorous Bleomycin-A5 injection for head and neck lymphangioma. Oral Surg Oral Med Oral Pathol. 1988;86:139
  6. Banieghbal B, Davies MR. Guidelines for the successful treatment of lymphangioma with OK-432. Eur J Pediatr Surg. 2003;13:103
  7. Okada A, Kubota A, Fukuzawa M, et al. Injection of bleomycin as a primary therapy of cystic lymphangioma. J Pediatr Surg. 1992;27:440
  8. Oxford J. Bleomycin therapy for cystic hygroma. J Pediatr Surg. 1995;30:1282
  9. Molitch HI, Unger EC, Witte CL, et al. Percutaneous sclerotherapy of lymphangiomas. Radiology. 1995;194:343
  10. Zulfiqar MA, Zaleha AM, Zakaria Z, et al. The treatment of neck lymphangioma with intralesional injection of bleomycin. Med J Malaysia. 1999;54:478
  11. Luzzatto C, Midrio P, Tchaprassian Z, et al. Sclerosing treatment of lymphangiomas with OK-432. Arch Dis Child. 2000;82:316
  12. Mason KP, Michna E, Zurakowski D, et al. Serum ethanol levels in children and adults after ethanol embolisation or sclerotherapy for vascular anomalies. Radiology. 2000;217:127
  13. Muir T, Kirsten M, Pourie P, et al. Intralesional bleomycin injection (IBI) treatment for haemangiomas and congenital vascular malformations. Pediatr Surg Int. 2004;19:766
  14. Zhao JH, Zhao YF, Chen XM, et al. Histological investigation of veins and venous malformations after injection of sclerosing agents. Asian J Oral Maxillofac Surg. 2002;14:226
  15. Rautio R, Keski-Nisula L, Laranne J, et al. Treatment of lymphangiomas with OK-432 (picibanil). Cardiovasc Intervent Radiol. 2003;26:31
  16. Peters DA, Courtemanche DJ, Heran MK, et al. Treatment of cystic lymphatic vascular malformations with OK-432 sclerotherapy. Plast Reconstr Surg. 2006;118:1441
  17. Zhao JH, Zhang WF, Zhao YF. Sclerotherapy of oral and facial venous malformations with use of pingyangmycin and/or sodium morrhuate. Int J Oral Maxillofac Surg. 2004;33:463
  18. Emery PJ, Bailey CM, Evans JN. Cystic hygroma of the head and neck (A review of 37 cases). J Laryngol Otol. 1984;98:613
  19. de Serres LM, Sie KC, Richardson MA. Lymphatic malformations of the head and neck (A proposal for staging). Arch Otolaryngol Head Neck Surg. 1995;121:577
  20. Fageeh N, Manoukian J, Tewfik T, et al. Management of head and neck lymphatic malformations in children. J Otolaryngol. 1997;26:253
  21. Riechelmann H, Muehlfay G, Keck T, et al. Total, subtotal, and partial surgical removal of cervicofacial lymphangiomas. Arch Otolaryngol Head Neck Surg. 1999;125:643
  22. Kennedy TL, Whitaker M, Pellitteri P, et al. Cystic hydroma/lymphangioma: A rational approach to management. Laryngoscope. 2001;111:1929
  23. Lei ZM, Huang XX, Sun ZJ, et al. Surgery of lymphatic malformations in oral and cervicofacial regions in children. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104:338
  24. Saijo M, Munro I, Mancer K. Lymphangioma: A long-term follow-up study. Plast Reconstr Surg. 1975;56:642
  25. Farmand M, Kuttenberger JJ. A new therapeutic concept for the treatment of cystic hygroma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996;81:389
  26. Ogita S, Tsuto T, Nakamura K, et al. OK-432 therapy in 64 patients with lymphangioma. J Pediatr Surg. 1994;29:784
  27. Cohen SR, Thompson JW. Lymphangiomas of the larynx in infants and children (A survey of pediatric lymphangioma). Ann Otol Rhinol Laryngol. 1986;127(suppl):1
  28. Sarihan H, Mocan H, Yildiz K, et al. new treatment with bleomycin for complicated cutaneous hemangioma in children. Eur J Pediatr Surg. 1997;7:158

PII: S0278-2391(08)01042-2

doi: 10.1016/j.joms.2008.06.046

Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 2 , Pages 251-256 , February 2009

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