Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 2 , Pages 286-291 , February 2009

Patients' Perception of Recovery After Third Molar Surgery Following Postoperative Treatment With Moxifloxacin Versus Amoxicillin and Clavulanic Acid: A Randomized, Double-Blind, Controlled Study

  • Jacobo Limeres, DDS, PhD

      Affiliations

    • Clinical Lecturer, Special Needs Unit, School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Limeres: Special Needs Unit, School of Medicine and Dentistry, Santiago de Compostela University, C/Entrerrios sn, 15782 Santiago de Compostela, Spain
    • ,
  • Jacinto F. Sanromán, MD, PhD

      Affiliations

    • Head of Department, Department of Maxillofacial Surgery, Policlínico Vigo S.A. Medical Center, Vigo, Spain
    • ,
  • Inmaculada Tomás, DDS, PhD

      Affiliations

    • Research Lecturer, Special Needs Unit, School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain
    • ,
  • Pedro Diz, MD, DDS, PhD

      Affiliations

    • Senior Lecturer, Special Needs Unit, School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain

References 

  1. Peterson LJ. Antibiotic prophylaxis against wound infections in oral and maxillofacial surgery. J Oral Maxillofac Surg. 1990;48:617
  2. Lawler B, Sambrook PJ, Goss AN. Antibiotic prophylaxis for dentoalveolar surgery: Is it indicated?. Aust Dent J. 2005;50(Suppl):S54
  3. Hedström L, Sjögren P. Effect estimates and methodological quality of randomized controlled trials about prevention of alveolar osteitis following tooth extraction: A systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103:8
  4. Perrott DH, Yuen JP, Andresen RV, et al. Office-based ambulatory anesthesia: Outcomes of clinical practice of oral and maxillofacial surgeons. J Oral Maxillofac Surg. 2003;61:983
  5. Zeitler DL. Prophylactic antibiotics for third molar surgery: A dissenting opinion. J Oral Maxillofac Surg. 1995;53:61
  6. Hill M. No benefit from prophylactic antibiotics in third molar surgery. Evid Based Dent. 2005;6:10
  7. Poeschl PW, Eckel D, Poeschl E. Postoperative prophylactic antibiotic treatment in third molar surgery—A necessity?. J Oral Maxillofac Surg. 2004;62:3
  8. Falconer DT, Roberts EE. Report of an audit into third molar exodontia. Br J Oral Maxillofac Surg. 1992;30:183
  9. Haug RH, Perrott DH, Gonzalez ML, et al. The American Association of Oral and Maxillofacial Surgeons Age-Related Third Molar Study. J Oral Maxillofac Surg. 2005;63:1106
  10. Gutiérrez JL, Bagán JV, Bascones A, et al. Consensus document on the use of antibiotic prophylaxis in dental surgery and procedures. Med Oral Pathol Oral Cir Bucal. 2006;11:E188
  11. Lacasa JM, Jiménez JA, Ferrás V, et al. Prophylaxis versus pre-emptive treatment for infective and inflammatory complications of surgical third molar removal: A randomized, double-blind, placebo-controlled, clinical trial with sustained release amoxicillin/clavulanic acid (1000/62.5 mg). Int J Oral Maxillofac Surg. 2007;36:321
  12. Greene JC, Vermillion JR. The oral hygiene index: A method for classifying oral hygiene status. J Am Dent Assoc. 1960;61:172
  13. Foy SP, Shugars DA, Phillips C, et al. The impact of intravenous antibiotics on health-related quality of life outcomes and clinical recovery after third molar surgery. J Oral Maxillofac Surg. 2004;62:15
  14. Arteagoitia I, Diez A, Barbier L, et al. Efficacy of amoxicillin/clavulanic acid in preventing infectious and inflammatory complications following impacted mandibular third molar extraction. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:11
  15. Beirne OR. Postoperative antibiotics do not improve clinical outcomes following removal of impacted mandibular third molars. J Evid Based Dent Pract. 2005;5:14
  16. Limeres J, Tomás I, Álvarez M, et al. Empirical antimicrobial therapy for odontogenic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:263
  17. Tomás M, Limeres J, Álvarez M, et al. Susceptibilidad in vitro a moxifloxacino de bacterias aisladas en abscesos dentales. Enferm Infecc Microbiol Clin. 2003;21(Suppl 1):67
  18. Sobottka I, Cachovan G, Stürenburg E, et al. In vitro activity of moxifloxacin against bacteria isolated from odontogenic infections. Antimicrob Agents Chemother. 2002;46:4019
  19. Milazzo I, Blandino G, Musumeci R, et al. Antibacterial activity of moxifloxacin against periodontal anaerobic pathogens involved in systemic infections. Int J Antimicrob Agents. 2002;20:451
  20. Kuriyama T, Karasawa T, Nakagawa K, et al. Bacteriologic features and antimicrobial susceptibility in isolates from orofacial odontogenic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;90:600
  21. Moore PA, Nahouraii HS, Zovko JG, et al. Dental therapeutic practice patterns in the U.S. (II. Analgesics, corticosteroids, and antibiotics). Gen Dent. 2006;54:201
  22. White RP, Shugars DA, Shafer DM, et al. Recovery after third molar surgery: Clinical and health-related quality of life outcomes. J Oral Maxillofac Surg. 2003;61:535
  23. Conrad SM, Blakey GH, Shugars DA, et al. Patients' perception of recovery after third molar surgery. J Oral Maxillofac Surg. 1999;57:1288
  24. Ruta DA, Bissias E, Ogston S, et al. Assessing health outcomes after extraction of third molars: The Postoperative Symptom Severity (PoSSe) Scale. Br J Oral Maxillofac Surg. 2000;38:480
  25. Sekhar CH, Narayanan V, Baig MF. Role of antimicrobials in third molar surgery: Prospective, double blind, randomized, placebo-controlled clinical study. Br J Oral Maxillofac Surg. 2001;39:134
  26. Bartlett JG. Antibiotic-associated diarrhea. Clin Infect Dis. 1992;15:573
  27. Wiström J, Norrby SR, Myhre EB, et al. Frequency of antibiotic-associated diarrhoea in 2462 antibiotic-treated hospitalized patients: A prospective study. J Antimicrob Chemother. 2001;47:43
  28. Oliphant CM, Green GM. Quinolones: A comprehensive review. Am Fam Physician. 2002;65:455
  29. Colorado-Bonnin M, Valmaseda-Castellón E, Berini-Aytés L, et al. Quality of life following lower third molar removal. Int J Oral Maxillofac Surg. 2006;35:343
  30. Van Gool AV, Ten Bosch JJ, Boering G. Clinical consequences of complaints and complications after removal of the mandibular third molar. Int J Oral Maxillofac Surg. 1977;6:29
  31. Berge TI. Inability to work after surgical removal of mandibular third molars. Acta Odontol Scand. 1997;55:64
  32. Bergdahl M, Hedström L. Metronidazole for the prevention of dry socket after removal of partially impacted mandibular third molar: A randomised controlled trial. Br J Oral Maxillofac Surg. 2004;42:555
  33. Ishihama K, Kimura T, Yasui Y, et al. Azithromycin as prophylaxis for the prevention of postoperative infection in impacted mandibular third-molar surgery. J Infect Chemother. 2006;12:31

PII: S0278-2391(08)01069-0

doi: 10.1016/j.joms.2008.06.061

Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 2 , Pages 286-291 , February 2009

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