A Clinicopathologic Correlation in the Diagnosis of Periradicular Lesions of Extracted Teeth

Omoregie, Osawe Felix; Saheeb, Birch Dauda O.; Odukoya, Onatolu; Ojo, Michael Akin

doi:10.1016/j.joms.2008.07.020

« Previous Next »Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 7 , Pages 1387-1391, July 2009

A Clinicopathologic Correlation in the Diagnosis of Periradicular Lesions of Extracted Teeth

Osawe Felix Omoregie, BDS, FWACS
- Lecturer 1, Department of Oral and Maxillofacial Surgery and Pathology, College of Medical Sciences, University of Benin; and Consultant, Oral Pathologist, Department of Oral and Maxillofacial Surgery and Pathology, University of Benin Teaching Hospital, Benin City, Nigeria
- Address correspondence and reprint requests to Dr Omoregie: University of Benin, University of Benin Teaching Hospital, Oral and Maxillofacial Surgery and Pathology, Ugbowo, Benin City, Edo State, Nigeria
Birch Dauda O. Saheeb, BDS, FWACS, FDSRCS
- Associate Professor, Department of Oral and Maxillofacial Surgery and Pathology, College of Medical Sciences, University of Benin; and Consultant, Oral and Maxillofacial Surgeon and Head of Department, University of Benin Teaching Hospital, Benin City, Nigeria
Onatolu Odukoya, BDS, MMSc, FMCDS, FWACS
- Professor, College of Medicine, University of Lagos; and Consultant, Oral Pathologist, Department of Oral Pathology and Oral Biology, Lagos University Teaching Hospital, Lagos, Nigeria
Michael Akin Ojo, BDS, MMedSc, DMR
- Professor, Department of Oral and Maxillofacial Surgery and Pathology, College of Medical Sciences, University of Benin; and Consultant, Oral Pathologist, Department of Oral and Maxillofacial Surgery and Pathology, University of Benin Teaching Hospital, Benin City, Nigeria

Purpose

We aimed to determine the contributory percentage of histopathologic diagnoses of routine biopsies and to ascertain the possible indicators for histopathologic examination to confirm the clinical diagnosis of periradicular lesions of extracted teeth.

Patients and Methods

This was a prospective study carried out over a period of 8 months on patients who had single tooth extraction and routine histopathologic examination of recoverable periradicular tissues from extracted teeth.

Results

A total of 136 patients participated in this study. There was a male/female incidence ratio of 3:2 and most of the patients with histopathologically diagnosed lesions were within the first, second, and third decades of life (n = 49, 36.0%). Seventy-five (55.2%) cases had histopathologically diagnosed periradicular lesions, which were mostly periapical abscess (n = 30, 22.8%) and inflammatory (periapical) granuloma (n = 23, 16.9%). Some clinical and radiologic features were associated significantly with histopathologic diagnosis of some periradicular lesions (P < .05). There also was a significant correlation of clinical diagnosis with histopathologic diagnosis of inflammatory (periapical) granuloma, periapical abscess, chronic osteomyelitis, and Burkitt's lymphoma (P < .05).

Conclusions

This study shows a higher contributory percentage of histopathologic diagnoses after routine biopsies, compared to previous reports from selected biopsies of periradicular lesions. We identified clinical indicators for predicting possible histopathologic diagnosis of some periradicular lesions, in particular, those that predict possible histologic diagnosis of neoplastic periradicular lesions.