Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 3 , Pages 501-506 , March 2009

Evaluation of Pluripotency in Human Dental Pulp Cells

  • Noriaki Koyama, DDS

      Affiliations

    • Graduate Student, Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    • ,
  • Yasunori Okubo, DDS, PhD

      Affiliations

    • Lecturer, Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Okubo: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan
    • ,
  • Kazumasa Nakao, DDS

      Affiliations

    • Graduate Student, Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
    • ,
  • Kazuhisa Bessho, DDS, DMsc

      Affiliations

    • Professor and Chairman, Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

References 

  1. Gronthos S, Mankani M, Brahim J, et al. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA. 2000;97:13625
  2. Spradling A, Drummond-Barbosa D, Kai T. Stem cells find their niche. Nature. 2001;414:98
  3. Gage FH. Mammalian neural stem cells. Science. 2000;287:1433
  4. Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science. 1997;276:71
  5. Weissman IL. Translating stem and progenitor cell biology to the clinic: Barriers and opportunities. Science. 2000;287:1442
  6. Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284:143
  7. Toma JG, Akhavan M, Fernandes KJ, et al. Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nat Cell Biol. 2001;3:778
  8. Zhang W, Walboomers XF, Shi S, et al. Multilineage differentiation potential of stem cells derived from human dental pulp after cryopreservation. Tissue Eng. 2006;12:2813
  9. Miura M, Gronthos S, Zhao M, et al. SHED: Stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA. 2003;100:5807
  10. Gronthos S, Brahim J, Li W, Fisher LW. Stem cell properties of human dental pulp stem cells. J Dent Res. 2002;81:531
  11. Okubo Y, Bessho K, Fujimura K, et al. In vitro and in vivo studies of a bone morphogenetic protein-2 expressing adenoviral vector. J Bone Joint Surg Am. 2001;83:99
  12. Okubo Y, Bessho K, Fujimura K, et al. Expression of bone morphogenetic protein-2 via adenoviral vector in C2C12 myoblasts induces differentiation into the osteoblast lineage. Biochem Biophys Res Commun. 1999;262:739
  13. Carrington JL, Chen P, Yanagishita M, et al. Osteogenin (bone morphogenetic protein-3) stimulates cartilage formation by chick limb bud cells in vitro. Dev Biol. 1991;146:406
  14. Hata R, Senoo H. L-ascorbic acid 2-phosphate stimulates collagen accumulation, cell proliferation, and formation of a 3-dimensional tissuelike substance by skin fibroblasts. J Cell Physiol. 1989;38:8
  15. Okubo Y, Bessho K, Reddi AH. Chondrogenesis by a human bone morphogenetic protein-2 expressing adenoviral vector. Recent Res Dev Biochem. 2006;6:151
  16. Gimble JM, Morgan C, Kelly K, et al. Bone morphogenetic proteins inhibit adipocyte differentiation by bone marrow stromal cells. J Cell Biochem. 1995;58:393
  17. Partridge NC, Alcorn D, Michelangeli VP, et al. Functional properties of hormonally responsive cultured normal and malignant rat osteoblastic cells. Endocrinology. 1981;108:213
  18. Kruger E, Thomson WM, Konthasinghe P. Third molar outcomes from age 18 to 26: Findings from a population based New Zealand longitudinal study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;92:150
  19. Olasoji HO, Odusanya SA. Comparative study of third molar impaction in rural and urban areas of South-Western Nigeria. Odontostomatol Trop. 2000;23:25
  20. Morris CR, Jerman AC. Panoramic radiographic survey: A study of embedded third molars. J Oral Surg. 1971;29:122
  21. Hugoson A, Kugelberg CF. The prevalence of third molars in a Swedish population (An epidemiological study). Community Dent Health. 1988;5:121
  22. Kaminishi RM, Kaminishi KS. New considerations in the treatment of compromised third molars. J Calif Dent Assoc. 2004;32:823
  23. Shi S, Bartold PM, Miura M, et al. The efficacy of mesenchymal stem cells to regenerate and repair dental structures. Orthod Craniofac Res. 2005;8:191
  24. Adams SL, Pallante KM, Niu Z, et al. Rapid induction of type X collagen gene expression in cultured chick vertebral chondrocytes. Exp Cell Res. 1991;193:190
  25. Wuthier RE, Register TC. Role of alkaline phosphatase: a polyfunctional enzyme in mineralizing tissues. In:  Butler WT editors. The Chemistry and Biology of Mineralized Tissue. Birmingham: Ebsco Media, Inc; 1985;p. 113
  26. Moerman EJ, Teng K, Lipschitz DA, et al. Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: The role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways. Aging Cell. 2004;3:379
  27. Tsukamoto Y, Fukutani S, Mori C, et al. In vitro cultivatin of human pulpal fibroblast strains—Permanent and deciduous teeth. Shika Kiso Igakkai Zasshi. 1989;31:372

PII: S0278-2391(08)01488-2

doi: 10.1016/j.joms.2008.09.011

Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 3 , Pages 501-506 , March 2009

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