Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 3 , Pages 589-592 , March 2009

The Role of Inferior Alveolar Nerve Involvement in Bisphosphonate-Related Osteonecrosis of the Jaw

  • Sven Otto, DDS

      Affiliations

    • Resident, Department of Oral and Maxillofacial Surgery, Ludwig-Maximilians-University, Munich, Germany
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Otto: Department of Oral and Maxillofacial Surgery, Ludwig-Maximilians-University, Lindwurmstrasse 2a, München, 80337 Germany
    • ,
  • Sigurd Hafner, DDS

      Affiliations

    • Resident, Department of Oral and Maxillofacial Surgery, Ludwig-Maximilians-University, Munich, Germany
    • ,
  • Knut A. Grötz, MD, DDS, PhD

      Affiliations

    • Professor and Head, Department of Oral and Maxillofacial Surgery, Horst-Schmidt-Klinikum, Wiesbaden, Germany

References 

  1. Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic. J Oral Maxillofac Surg. 2003;61:1115
  2. Yarom N, Yahalom R, Shoshani Y, et al. Osteonecrosis of the jaw induced by orally administered bisphosphonates: Incidence, clinical features, predisposing factors and treatment outcome. Osteoporos Int. 2007;18:1363
  3. Wang EP, Kaban LB, Strewler GJ, et al. Incidence of osteonecrosis of the jaw in patients with multiple myeloma and breast or prostate cancer on intravenous bisphosphonate therapy. J Oral Maxillofac Surg. 2007;65:1328
  4. Bamias A, Kastritis E, Bamia C, et al. Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: Incidence and risk factors. J Clin Oncol. 2005;23:8580
  5. Khosla S, Burr D, Cauley J, et al. Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2007;22:1479
  6. Reid IR, Bolland MJ, Grey AB. Is bisphosphonate-associated osteonecrosis of the jaw caused by soft tissue toxicity?. Bone. 2007;41:318
  7. Diel IJ, Fogelman I, Al Nawas B, et al. Pathophysiology, risk factors and management of bisphosphonate-associated osteonecrosis of the jaw: Is there a diverse relationship of amino- and non-aminobisphosphonates?. Crit Rev Oncol Hematol. 2007;64:198
  8. Vincent B. Sur un signe precoce de certaines osteites du maxillaire inferrieur de terminant par necrose. Rev Trimestr Suisse d'Odontol. 1896;6:148
  9. Thomson PJ, Rood JP. Mental nerve dysfunction: A symptom of diverse mandibular disease. Dent Update. 1995;22:271
  10. Baltensperger M, Gratz K, Bruder E, et al. Is primary chronic osteomyelitis a uniform disease? (Proposal of a classification based on a retrospective analysis of patients treated in the past 30 years). J Craniomaxillofac Surg. 2004;32:43
  11. Barrett AP, Buckley DJ. Selective anesthesias of peripheral branches of the trigeminal nerve due to odontogenic infection. Oral Surg Oral Med Oral Pathol. 1986;62:226
  12. Grotz KA, Al Nawas B, de Aguiar EG, et al. Treatment of injuries to the inferior alveolar nerve after endodontic procedures. Clin Oral Investig. 1998;2:73
  13. Morse DR. Infection-related mental and inferior alveolar nerve paresthesia: Literature review and presentation of two cases. J Endod. 1997;23:457
  14. Reboiras L, Garcia GA, Antunez LJ, et al. Anaesthesia of the right lower hemilip as a first manifestation of multiple myeloma (Presentation of a clinical case). Med Oral. 2001;6:168
  15. Zanglis A, Andreopoulos D, Dima M, et al. Jaw uptake of technetium-99 methylene diphosphonate in patients on biphosphonates: A word of caution. Hell J Nucl Med. 2007;10:177
  16. Weitzman R, Sauter N, Eriksen EF, et al. Critical review: Updated recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in cancer patients—May 2006. Crit Rev Oncol Hematol. 2007;62:148

PII: S0278-2391(08)01508-5

doi: 10.1016/j.joms.2008.09.028

Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 3 , Pages 589-592 , March 2009

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