Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 5, Supplement , Pages 71-74 , May 2009

Epidemiology of Bisphosphonate-Related Osteonecrosis of the Jaws: The Utility of a National Registry

  • Richard Gliklich, MD

      Affiliations

    • President, Outcome Sciences, Inc, Cambridge, MA
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Gliklich: Outcome Sciences, Inc, 201 Broadway, Cambridge, MA
    • ,
  • Jerome Wilson, PhD

      Affiliations

    • Director, Scientific Affairs, Outcome Sciences, Inc, Cambridge, MA

References 

  1. Shenker NG, Jawad ASM. Bisphosphonates and osteonecrosis of the jaw. Rheumatology. 2007;46:1049
  2. McKown K. Osteonecrosis. 2008 http://www.rheumatology.org/public/factsheets/osteonecrosis.aspAccessed July 28, 2008
  3. Woo S-B, Hellstein JW, Kalmar JR. Systematic review: Bisphosphonates and osteonecrosis of the jaws. Ann Intern Med. 2006;144:753
  4. Nancollas GH, Tang R, Phipps RJ, et al. Novel insights into actions of bisphosphonates on bone: Differences in interactions with hydroxyapatite. Bone. 2006;38:617
  5. Bilezikian JP. Osteonecrosis of the jaw—Do bisphosphonates pose a risk?. N Engl J Med. 2006;355:2278
  6. Bamias A, Kastritis E, Bamia C, et al. Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: Incidence and risk factors. J Clin Oncol. 2005;23:8580
  7. In:  Gliklich RE,  Dreyer NA editor. Registries for Evaluating Patient Outcomes: A User's Guide (AHRQ Publication No. 07-EHC001-1). Rockville, MD: Agency for Healthcare Research and Quality; 2007;
  8. Ruggiero S, Fantasia J, Carlson E. Bisphosphonate-related osteonecrosis of the jaw: Background and guidelines for diagnosis, staging and management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102:433
  9. Robinson NA. Biphosphonates: A word of caution. Ann Acad Med Singapore. 2004;33(suppl):S48
  10. Assouline-Dayan Y, Chang C, Greenspan A, et al. Pathogenesis and natural history of osteonecrosis. Semin Arthritis Rheum. 2002;32:94

 Dr Gliklich owns equity in Outcome Sciences, Inc. Dr Wilson states no financial arrangement or affiliation with a corporate organization or a manufacturer of a product discussed in this article.

PII: S0278-2391(09)00071-8

doi: 10.1016/j.joms.2009.01.005

Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 5, Supplement , Pages 71-74 , May 2009

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