Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 7 , Pages 1373-1377 , July 2009

Higher Bone Matrix Density Exists in Only a Subset of Patients With Bisphosphonate-Related Osteonecrosis of the Jaw

  • Matthew R. Allen, PhD

      Affiliations

    • Assistant Professor, Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Allen: Department of Anatomy and Cell Biology, 635 Barnhill Dr, MS-5035, Indianapolis, IN 46202
    • ,
  • Salvatore L. Ruggiero, DMD, MD

      Affiliations

    • Attending, New York Center for Orthognathic and Maxillary Surgery, Lake Success, NY, and Associate Professor, Department of Oral and Maxillofacial Surgery, School of Dental Medicine, The State University of New York, Stony Brook, NY

References 

  1. Khosla S, Burr D, Cauley J, et al. Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2007;22:1479
  2. American Association of Oral and Maxillofacial Surgeons. Position paper on bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg. 2007;65:369
  3. Woo SB, Hellstein JW, Kalmar JR. Systematic review: Bisphosphonates and osteonecrosis of the jaws. Ann Intern Med. 2006;144:753
  4. Lacy MQ, Dispenzieri A, Gertz MA, et al. Mayo Clinic consensus statement for the use of bisphosphonates in multiple myeloma. Mayo Clin Proc. 2006;81:1047
  5. Kuehn BM. Reports of adverse events from bone drugs prompt caution. JAMA. 2006;295:2833
  6. Mavrokokki T, Cheng A, Stein B, et al. Nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in Australia. J Oral Maxillofac Surg. 2007;65:415
  7. Ruggiero SL, Drew SJ. Osteonecrosis of the jaws and bisphosphonate therapy. J Dent Res. 2007;86:1013
  8. American Dental Association Council on Scientific Affairs. Dental management of patients receiving oral bisphosphonate therapy: Expert panel recommendations. J Am Dent Assoc. 2006;137:1144
  9. Ruggiero SL, Fantasia J, Carlson E. Bisphosphonate-related osteonecrosis of the jaw: Background and guidelines for diagnosis, staging and management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102:433
  10. Guerrero ME, Jacobs R, Loubele M, et al. State-of-the-art on cone beam CT imaging for preoperative planning of implant placement. Clin Oral Investig. 2006;10:1
  11. Chiandussi S, Biasotto M, Dore F, et al. Clinical and diagnostic imaging of bisphosphonate-associated osteonecrosis of the jaws. Dentomaxillofac Radiol. 2006;35:236
  12. Phal PM, Myall RWT, Assael LA, et al. Imaging findings of bisphosphonate-associated osteonecrosis of the jaws. AJNR Am J Neuroradiol. 2007;28:1139
  13. Bianchi SD, Scoletta M, Cassione FB, et al. Computerized tomographic findings in bisphosphonate-associated osteonecrosis of the jaw in patients with cancer. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104:249
  14. Raje N, Woo SB, Hande K, et al. Clinical, radiographic, and biochemical characterization of multiple myeloma patients with osteonecrosis of the jaw. Clin Cancer Res. 2008;14:2387

 The micro–computed tomography equipment used in this research was purchased through a National Institutes of Health equipment grant (S10-RR023710).

PII: S0278-2391(09)00437-6

doi: 10.1016/j.joms.2009.03.048

Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 7 , Pages 1373-1377 , July 2009

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