Journal of Oral and Maxillofacial Surgery
Volume 68, Issue 2 , Pages 243-253 , February 2010

Prevalence of Osteonecrosis of the Jaw in Patients With Oral Bisphosphonate Exposure

These data were presented in part at the 90th Annual Meeting of the Endocrine Society, San Francisco, CA, June 15-18, 2008.

  • Joan C. Lo, MD

      Affiliations

    • Research Scientist, Division of Research, Kaiser Permanente Northern California, Oakland, and Associate Clinical Professor, Department of Medicine, University of California, San Francisco, School of Medicine, San Francisco, CA
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Lo: Division of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA 94612
  • ,
  • Felice S. O'Ryan, DDS

      Affiliations

    • Director, Division of Maxillofacial Surgery, Kaiser Permanente Oakland Medical Center, Oakland, CA
  • ,
  • Nancy P. Gordon, ScD

      Affiliations

    • Research Scientist, Division of Research, Kaiser Permanente Northern California, Oakland, CA
  • ,
  • Jingrong Yang, MA

      Affiliations

    • Data Consultant, Division of Research, Kaiser Permanente Northern California, Oakland, CA
  • ,
  • Rita L. Hui, PharmD, MS

      Affiliations

    • Outcomes Research Scientist, Pharmacy Outcomes Research Group, Drug Information Services, Kaiser Permanente California, Oakland, CA
  • ,
  • Daniel Martin, DDS

      Affiliations

    • Resident, Division of Maxillofacial Surgery, Kaiser Permanente Oakland Medical Center, and Department of Oral and Maxillofacial Surgery, Highland General Hospital, Oakland, CA
  • ,
  • Matthew Hutchinson, DDS

      Affiliations

    • Resident, Division of Maxillofacial Surgery, Kaiser Permanente Oakland Medical Center, and Department of Oral and Maxillofacial Surgery, Highland General Hospital, Oakland, CA
  • ,
  • Phenius V. Lathon

      Affiliations

    • Project Manager, Division of Research, Kaiser Permanente Northern California, Oakland, CA
  • ,
  • Gabriela Sanchez

      Affiliations

    • Project Manager, Division of Research, Kaiser Permanente Northern California, Oakland, CA
  • ,
  • Paula Silver

      Affiliations

    • Project Manager, Division of Research, Kaiser Permanente Northern California, Oakland, CA
  • ,
  • Malini Chandra

      Affiliations

    • Senior Consulting Data Analyst, Division of Research, Kaiser Permanente Northern California, Oakland, CA
  • ,
  • Carolyn A. McCloskey, MD

      Affiliations

    • Epidemiologist, US Food and Drug Administration, Center for Drug Evaluation and Research, Office of Surveillance and Epidemiology, Silver Spring, MD
  • ,
  • Judy A. Staffa, PhD

      Affiliations

    • Associate Director for Regulatory Research, US Food and Drug Administration, Center for Drug Evaluation and Research, Office of Surveillance and Epidemiology, Silver Spring, MD
  • ,
  • Mary Willy, PhD

      Affiliations

    • Senior Risk Analyst, US Food and Drug Administration, Center for Drug Evaluation and Research, Office of Surveillance and Epidemiology, Silver Spring, MD
  • ,
  • Joe V. Selby, MD, MPH

      Affiliations

    • Director, Division of Research, Kaiser Permanente Northern California, Oakland, CA
  • ,
  • Alan S. Go, MD

      Affiliations

    • Research Scientist, Division of Research, Kaiser Permanente Northern California, Oakland, and Associate Professor, Departments of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, School of Medicine, San Francisco, CA
  • ,
  • Predicting Risk of Osteonecrosis of the Jaw with Oral Bisphosphonate Exposure (PROBE) Investigators

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 This study was funded by the US Food and Drug Administration (HHSF223200510008C), the National Institute of Child Health and Human Development at the National Institutes of Health (K12 HD052163), and the Kaiser Permanente Community Benefit Program; a portion of this study was also supported by the National Center for Research Resources at the National Institutes of Health (UCSF-CTSI UL1 RR024131).

 J. Lo previously received research funding from Novartis; D. Martin previously owned stock in Merck & Company, Incorporated; a household family member of N. Gordon previously owned stock in Novartis Pharmaceuticals; a nonhousehold family member of F. O'Ryan is employed by Roche Laboratories; A. Go previously received research funding from Amgen and currently receives research funding from GlaxoSmithKline.

 The contents of this publication are solely the responsibility of the authors and do not represent the official views of the Food and Drug Administration or the National Institutes of Health.

PII: S0278-2391(09)00441-8

doi: 10.1016/j.joms.2009.03.050

Journal of Oral and Maxillofacial Surgery
Volume 68, Issue 2 , Pages 243-253 , February 2010