Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 9 , Pages 1884-1888 , September 2009

Does Perioperative Glucocorticosteroid Treatment Correlate With Disturbance in Surgical Wound Healing After Treatment of Facial Fractures? A Retrospective Study

  • Hanna Thorén, MD, DDS, PhD

      Affiliations

    • Consultant and Lecturer, Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital, and Department of Oral and Maxillofacial Surgery, Institute of Dentistry, Helsinki University, Helsinki, Finland; and Department of Cranio-Maxillofacial Surgery, Bern University Hospital and University of Bern, Bern, Switzerland
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Thorén: Department of Cranio-Maxillofacial Surgery, Bern University Hospital, Inselspital, Ch-3010, Bern, Switzerland
    • ,
  • Johanna Snäll, DDS

      Affiliations

    • Resident, Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital, and Department of Oral and Maxillofacial Surgery, Institute of Dentistry, Helsinki University, Helsinki, Finland
    • ,
  • Eeva Kormi, DDS

      Affiliations

    • Resident, Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital, and Department of Oral and Maxillofacial Surgery, Institute of Dentistry, Helsinki University, Helsinki, Finland
    • ,
  • Laura Numminen, DDS

      Affiliations

    • Associate Investigator, Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital, and Department of Oral and Maxillofacial Surgery, Institute of Dentistry, Helsinki University, Helsinki, Finland
    • ,
  • Reto Fäh, DDS

      Affiliations

    • Associate Investigator, Department of Cranio-Maxillofacial Surgery, Bern University Hospital and University of Bern, Bern, Switzerland
    • ,
  • Tateyuki Iizuka, MD, DDS, PhD, FEBOMFS

      Affiliations

    • Professor, Head, and Chair, Department of Cranio-Maxillofacial Surgery, Bern University Hospital and University of Bern, Bern, Switzerland
    • ,
  • Christian Lindqvist, MD, DDS, PhD

      Affiliations

    • Professor, Head, and Chair, Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital, and Department of Oral and Maxillofacial Surgery, Institute of Dentistry, Helsinki University, Helsinki, Finland
    • ,
  • Jyrki Törnwall, MD, DDS, PhD

      Affiliations

    • Consultant, Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital, and Department of Oral and Maxillofacial Surgery, Institute of Dentistry, Helsinki University, Helsinki, Finland

References 

  1. Assimes T, Lessard ML. The use of perioperative corticosteroids in craniomaxillofacial surgery. Plast Reconstr Surg. 1999;103:313
  2. Esen E, Taşar F, Akhan O. Determination of the anti-inflammatory effects of methylprednisolone on the sequelae of third molar surgery. J Oral Maxillofac Surg. 1999;57:1201
  3. Bamgbose BO, Akinwande JA, Adeyemo WL, et al. Effects of co-administered dexamethasone and diclofenac potassium on pain, swelling and trismus following third molar surgery (Head and face). Medicine. 2005;1:11
  4. Buyukkurt MC, Gungormus M, Kaya O. The effect of single dose prednisolone with and without diclofenac on pain, trismus, and swelling after removal of mandibular third molars. J Oral Maxillofac Surg. 2006;64:1761
  5. Graziani F, D'Aiuto F, Arduino PG, et al. Perioperative dexamethasone reduces post-surgical sequelae of wisdom tooth removal (A split-mouth randomized double-masked clinical trial). Int J Oral Maxillofac Surg. 2006;35:241
  6. Grossi GB, Maiorana C, Garramone RA, et al. Effect of submucosal injection of dexamethasone on postoperative discomfort after third molar surgery: A prospective study. J Oral Maxillofax Surg. 2007;65:2,218,
  7. Weber CR, Griffin JM. Evaluation of dexamethasone for reducing postoperative edema and inflammatory response after orthognathic surgery. J Oral Maxillofac Surg. 1994;52:35
  8. Flood TR, McManners J, El Attar A, et al. Randomized prospective study of the influence of steroids on postoperative eye-opening after exploration of the orbital floor. Br J Oral Maxillofac Surg. 1999;37:312
  9. Wong GKC, Poon WS, Chiu KH. Steroid-induced avascular necrosis of the hip in neurosurgical patients: Epidemiological study. Aust N Z J Surg. 2005;75:409
  10. Fleming PS, Flood TR. Interesting case: Steroid-induced psychosis after orthognathic surgery. Br J Oral Maxillofac Surg. 2005;43:419
  11. Wicke C, Halliday B, Allen D, et al. Effects of steroids and retinoids on wound healing. Arch Surg. 2000;135:1265
  12. Islamoglu K, Coskunfirat OK, Tetik G, et al. Complications and removal rates of miniplates and screws used for maxillofacial fractures. Ann Plast Surg. 2002;48:265
  13. Lamphier J, Ziccardi V, Ruvo A, et al. Complications after mandibular fractures in an urban teaching center. J Oral Maxillofac Surg. 2003;61:745
  14. Murthy AS, Lehman JA. Symptomatic plate removal in maxillofacial trauma (A review of 76 cases). Ann Plast Surg. 2005;55:603
  15. Furr AM, Schweinfurth JM, May WL. Factors associated with long-term complications after repair of mandibular fractures. Laryngoscope. 2006;116:427
  16. Bakathir AA, Margasahayam MV, Al-Ismaily M. Removal of bone plates in patients with maxillofacial trauma: A retrospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105:e32

PII: S0278-2391(09)00593-X

doi: 10.1016/j.joms.2009.04.089

Journal of Oral and Maxillofacial Surgery
Volume 67, Issue 9 , Pages 1884-1888 , September 2009

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