Logo
Search for

Articles in Press

Return to articles in press list

Significance of Dynamic Magnetic Resonance Sialography in Prognostic Evaluation of Saline Solution Irrigation of the Parotid Gland for the Treatment of Xerostomia

Manabu Habu, DDS, PhD, Tatsuro Tanaka, DDS, PhD, Taiki Tomoyose, DDS, PhD, Kentaro Ono, DDS, PhD§, Toshihiro Anzai, DDS, PhD, Yuu Ozaki, DDS, PhD, Izumi Yoshioka, DDS, PhD⁎⁎, Yoshihiro Yamashita, DDS, PhD††, Masaaki Kodama, DDS‡‡, Noriaki Yamamoto, DDS, PhD§§, Masufumi Oda, DDS∥∥, Nao Wakasugi, DDS, PhD¶¶, Shinobu Matsumoto, DDS, PhD⁎⁎⁎, Tetsu Takahashi, DDS, PhD†††, Kiyotoshi Inenaga, PhD‡‡‡, Kazuhiro Tominaga, DDS, PhD§§§, Yasuhiro Morimoto, DDS, PhD∥∥∥Corresponding Author Informationemail address

published online 16 November 2009.
Corrected Proof

Purpose

To evaluate the clinical significance of dynamic magnetic resonance (MR) sialographic images in prognostic evaluation of saline solution irrigation of the parotid gland for the treatment of xerostomia.

Materials and Methods

Morphologic findings and functional parameters were evaluated by use of dynamic MR sialography before saline solution irrigation of the parotid gland for the treatment of xerostomia in 17 patients. In addition, the MR sialographic data before the saline solution irrigation treatment in patients with improvement of salivary secretion and the sensation of dry mouth after irrigation treatment were compared with data in patients without improvement.

Results

The maximum changing ratio in the group of patients with improvement after treatment was significantly higher (P = .042) than that in the group of patients without improvement. In addition, high correlations were found between the changing ratio and improvement on the visual analog scale for dry mouth sensation after treatment (Pearson r = 0.63, P = .001) and improvement of salivary flow rate (Pearson r = 0.77, P = .001). Moreover, in 12 patients with improvement of salivary flow rate after the saline solution irrigation treatment, the maximum changing ratio before the saline solution irrigation treatment was over 1.2. However, no significant differences in other parameters, including the detectable ductal area, were found between the group of patients with improvement after treatment and the group without improvement.

Conclusions

Our study suggests that dynamic MR sialography might be useful for the prognostic evaluation of saline solution irrigation of the parotid gland for the treatment of xerostomia.

 Assistant Professor, Department of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Science

 Lecturer, Department of Oral Diagnostic Science, Division of Diagnostic Radiology

 Assistant Professor, Department of Oral and Maxillofacial Surgery, Division of Oral and Maxillofacial Reconstructive Surgery

§ Assistant Professor, Department of Biosciences, Division of Physiology

 Associate Professor, Department of Health Promotion, Division of Community Oral Health Science

 Assistant Professor, Department of Control of Physical Functions, Division of Oral Care and Rehabilitation

⁎⁎ Associate Professor, Department of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Science

†† Associate Professor, Department of Oral and Maxillofacial Surgery, Division of Oral and Maxillofacial Reconstructive Surgery

‡‡ Assistant Professor, Department of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Science

§§ Assistant Professor, Department of Oral and Maxillofacial Surgery, Division of Oral and Maxillofacial Reconstructive Surgery

∥∥ Postgraduate Student, Department of Oral Diagnostic Science, Division of Diagnostic Radiology

¶¶ Assistant Professor, Department of Oral Diagnostic Science, Division of Diagnostic Radiology

⁎⁎⁎ Assistant Professor, Department of Oral Diagnostic Science, Division of Diagnostic Radiology

††† Professor, Department of Oral and Maxillofacial Surgery, Division of Oral and Maxillofacial Reconstructive Surgery

‡‡‡ Professor, Department of Biosciences, Division of Physiology

§§§ Assistant Professor, Department of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Science

∥∥∥ Professor, Department of Oral Diagnostic Science, Division of Diagnostic Radiology

Corresponding Author InformationAddress correspondence and reprint requests to Dr Morimoto: Division of Diagnostic Radiology, Department of Oral Diagnostic Science, Kyushu Dental College, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Fukuoka 803-8580, Japan

 Received from Kyushu Dental College, Kitakyushu, Japan

 Supported in part by Grants-in-Aid for Scientific Research from the Ministry of Education, Science, Sports and Culture of Japan and from the President of Kyushu Dental College to Y.M.

PII: S0278-2391(09)00609-0

doi:10.1016/j.joms.2009.04.110