Journal of Oral and Maxillofacial Surgery
Volume 68, Issue 4 , Pages 797-804 , April 2010

Occurrence of Bisphosphonate-Related Osteonecrosis of the Jaw After Surgical Tooth Extraction

  • Giorgia Saia, MD

      Affiliations

    • Assistant Professor, Unit of Maxillofacial Surgery, University of Padova, Padua, Italy
    • ,
  • Stella Blandamura, MD

      Affiliations

    • Assistant Professor, Institute of Pathology, University of Padova, Padua, Italy
    • ,
  • Giordana Bettini, MD

      Affiliations

    • Resident, Section of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy
    • ,
  • Anita Tronchet, MD

      Affiliations

    • Resident, Unit of Maxillofacial Surgery, University of Padova, Padua, Italy
    • ,
  • Andrea Totola, DMD

      Affiliations

    • Section of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy
    • ,
  • Giorgio Bedogni, MD

      Affiliations

    • Senior Researcher, Clinical Epidemiology Unit, Liver Research Center, Trieste, Italy
    • Corresponding Author InformationAddress correspondence and reprint requests to Dr Bedogni: Section of Oral and Maxillofacial Surgery, Department of Biological and Morphological Sciences, University of Verona, Hospital GB Rossi, Piazzale LA Scuro 10, 37134 Verona, Italy
    • ,
  • Giuseppe Ferronato, MD

      Affiliations

    • Full Professor, Unit of Maxillofacial Surgery, University of Padova, Padua, Italy
    • ,
  • Pier Francesco Nocini, MD, DDS

      Affiliations

    • Full Professor, Section of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy
    • ,
  • Alberto Bedogni, MD

      Affiliations

    • Assistant Professor, Section of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy

References 

  1. Ruggiero SL, Dodson TB, Assael LA, et al. American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws—2009 update. J Oral Maxillofac Surg. 2009;67:2
  2. Khosla S, Burr D, Cauley J, et al. Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2007;22:1479
  3. Kyrgidis A, Vahtsevanos K, Koloutsos G, et al. Bisphosphonate-related osteonecrosis of the jaws: A case-control study of risk factors in breast cancer patients. J Clin Oncol. 2008;26:4634
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  8. Bedogni A, Blandamura S, Lokmic Z, et al. Bisphosphonate-associated jawbone osteonecrosis: A correlation between imaging techniques and histopathology. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105:358
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  13. Bamias A, Kastritis E, Bamia C, et al. Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: Incidence and risk factors. J Clin Oncol. 2005;23:8580
  14. Mavrokokki T, Cheng A, Stein B, et al. Nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in Australia. J Oral Maxillofac Surg. 2007;65:415
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  21. Edwards BJ, Hellstein JW, Jacobsen PL, et al. Updated recommendations for managing the care of patients receiving oral bisphosphonate therapy: An advisory statement from the American Dental Association Council on Scientific Affairs. J Am Dent Assoc. 2008;139:1674
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  25. Marx RE, Sawatari Y, Fortin M, et al. Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: Risk factors, recognition, prevention, and treatment. J Oral Maxillofac Surg. 2005;63:1567
  26. Ruggiero SL, Drew SJ. Osteonecrosis of the jaws and bisphosphonate therapy. J Dent Res. 2007;86:1013
  27. Bettini G, Bedogni A, Saia G, et al. Surgical treatment of bisphosphonate-related osteonecrosis. J Craniomaxillofac Surg. 2008;36(suppl 1):37
  28. Reid IR, Cundy T. Osteonecrosis of the jaw. Skeletal Radiol. 2009;38:5
  29. Treister N, Sheehy N, Bae EH, et al. Dental panoramic radiographic evaluation in bisphosphonate-associated osteonecrosis of the jaws. Oral Dis. 2009;15:88
  30. Junquera L, Gallego L. Nonexposed bisphosphonate-related osteonecrosis of the jaws: Another clinical variant?. J Oral Maxillofac Surg. 2008;66:1516

PII: S0278-2391(09)01999-5

doi: 10.1016/j.joms.2009.10.026

Journal of Oral and Maxillofacial Surgery
Volume 68, Issue 4 , Pages 797-804 , April 2010

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